Knee Surgery, Sports Traumatology, Arthroscopy

, Volume 24, Issue 6, pp 1763–1774 | Cite as

The role of meniscal tissue in joint protection in early osteoarthritis

  • Rene Verdonk
  • Henning Madry
  • Nogah Shabshin
  • Florian Dirisamer
  • Giuseppe M. Peretti
  • Nicolas Pujol
  • Tim Spalding
  • Peter Verdonk
  • Romain Seil
  • Vincenzo Condello
  • Berardo Di Matteo
  • Johannes Zellner
  • Peter AngeleEmail author


It is widely accepted that partial meniscectomy leads to early onset of osteoarthritis (OA). A strong correlation exists between the amount and location of the resected meniscus and the development of degenerative changes in the knee. On the other hand, osteoarthritic changes of the joint alter the structural and functional integrity of meniscal tissue. These alterations might additionally compromise the limited healing capacity of the meniscus. In young, active patients without cartilage damage, meniscus therapy including partial meniscectomy, meniscus suture, and meniscus replacement has proven beneficial effects in long-term studies. Even in an early osteoarthritic milieu, there is a relevant regenerative potential of the meniscus and the surrounding cartilage. This potential should be taken into account, and meniscal surgery can be performed with the correct timing and the proper indication even in the presence of early OA.

Level of evidence IV.


Meniscus Early OA Partial meniscectomy Meniscal repair Scaffold Allograft 


Compliance with ethical standards

Conflict of interest

Some of the authors have relationship with Orteq Sports Medicine, London, UK, and Active Implants, Memphis, USA.


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Copyright information

© European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2016

Authors and Affiliations

  • Rene Verdonk
    • 1
  • Henning Madry
    • 2
  • Nogah Shabshin
    • 3
    • 4
  • Florian Dirisamer
    • 5
  • Giuseppe M. Peretti
    • 6
    • 7
  • Nicolas Pujol
    • 8
  • Tim Spalding
    • 9
  • Peter Verdonk
    • 10
  • Romain Seil
    • 11
  • Vincenzo Condello
    • 12
  • Berardo Di Matteo
    • 13
  • Johannes Zellner
    • 14
  • Peter Angele
    • 14
    • 15
    Email author
  1. 1.Ghent UniversityGhentBelgium
  2. 2.Department of Orthopaedic SurgerySaarland University Medical CenterHomburgGermany
  3. 3.Department of RadiologyCarmel Medical CenterHaifaIsrael
  4. 4.Department of RadiologyHospital of University of PennsylvaniaPhiladelphiaUSA
  5. 5.Orthopädie und SportchirurgieSchloss PuchenauLinz-PuchenauAustria
  6. 6.IRCCS Istituto Ortopedico GaleazziMilanItaly
  7. 7.Department of Biomedical Sciences for HealthUniversity of MilanMilanItaly
  8. 8.Centre hospitalier de VersaillesLe ChesnayFrance
  9. 9.Department of OrthopaedicsUniversity Hospital of Coventry and WarwickshireRugbyUK
  10. 10.Antwerp Orthopedic CenterMonica HospitalsAntwerpBelgium
  11. 11.Clinique d’Eich and Sports Medicine Research Laboratory, Department of Orthopaedic Surgery, Centre Hospitalier LuxembourgLuxembourg Institute of HealthLuxembourgLuxembourg
  12. 12.Dipartimento di Ortopedia - Responsabile di Struttura Semplice di Traumatologia delloSport Knee Surgery and Sports Traumatology Ospedale Sacro Cuore - Don Calabria Via DonNegrar VeronaItaly
  13. 13.II Orthopaedic Clinic and Biomechanics LabIstituto Ortopedico RizzoliBolognaItaly
  14. 14.Department of Trauma SurgeryUniversity Medical Center RegensburgRegensburgGermany
  15. 15.Sporthopaedicum RegensburgRegensburgGermany

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