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Platelet-rich plasma: does it help reduce tunnel widening after ACL reconstruction?

  • Antonio VadalàEmail author
  • Raffaele Iorio
  • Angelo De Carli
  • Matteo Ferretti
  • Daniele Paravani
  • Ludovico Caperna
  • Carlo Iorio
  • Andrea Gatti
  • Andrea Ferretti
Knee

Abstract

Purpose

The purpose of this study was to evaluate the efficacy of platelet-rich plasma (PRP) in reducing femoral and tibial tunnel enlargement in patients operated on for anterior cruciate ligament reconstruction with hamstrings.

Methods

Forty male patients, in which both femoral and tibial 9-mm tunnels were performed because of the graft size, were enrolled in this prospective study. They were randomly assigned to group A (20 patients, PRP group) and group B (20 patients, control group). All patients were followed up at a median of 14.7 months (range 10–16 months), with a physical examination, the Tegner, Lysholm and objective IKDC scoring scales, and with the KT-1000 arthrometer. Moreover, they underwent a CT evaluation in order to assess the amount of tunnel enlargement.

Results

Femoral tunnel diameter increased from 9.0 ± 0.1 mm to 9.8 ± 0.3 mm in group A (p = 0.032) and from 9.0 ± 0.1 mm to 9.4 ± 0.5 mm in group B (p = 0.043). Tibial tunnel diameter increased from 9.0 ± 0.2 mm to 10.9 ± 0.2 mm in group A (p = 0.029) and from 9.1 ± 0.1 mm to 10.1 ± 0.4 mm in group B (p = 0.028). Physical examination as well as the evaluation scales used showed no differences between the two groups.

Conclusions

The use of PRP does not seem to be effective in preventing tunnel enlargement.

Level of evidence

Therapeutic study, Level II.

Keywords

Platelet-rich plasma Tunnel enlargement ACL reconstruction CT scan 

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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Antonio Vadalà
    • 1
    Email author
  • Raffaele Iorio
    • 1
  • Angelo De Carli
    • 1
  • Matteo Ferretti
    • 1
  • Daniele Paravani
    • 1
  • Ludovico Caperna
    • 1
  • Carlo Iorio
    • 1
  • Andrea Gatti
    • 1
  • Andrea Ferretti
    • 1
  1. 1.Orthopaedic Unit and “Kirk Kilgour” Sports Injury Centre, S. Andrea HospitalUniversity of Rome “La Sapienza”RomeItaly

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