Patellofemoral and tibiofemoral articular cartilage and subchondral bone health following arthroscopic partial medial meniscectomy
- First Online:
- 351 Downloads
To examine articular cartilage and subchondral bone changes in tibiofemoral and patellofemoral joints following partial medial meniscectomy.
For this cross-sectional study, 158 patients aged 30–55 years, without evidence of knee osteoarthritis at arthroscopic partial medial meniscectomy (APMM), and 38 controls were recruited. MRI was performed once on the operated knee for each subcohort of 3 months, 2 or 4 years post-surgery, and the randomly assigned knee of the controls. Cartilage volume, cartilage defects, and bone size were assessed using validated methods.
Compared with controls, APMM patients had more prevalent cartilage defects in medial tibiofemoral (OR = 3.17, 95%CI 1.24–8.11) and patellofemoral (OR = 13.76, 95%CI 1.52–124.80) compartments, and increased medial tibial plateau bone area (B = 143.8, 95%CI 57.4–230.2). Time from APMM was positively associated with cartilage defect prevalence in medial tibiofemoral (OR = 1.02, 95%CI 1.00–1.03) and patellofemoral (OR = 1.04, 95%CI 1.01–1.07) compartments, and medial tibial plateau area (B = 2.5, 95%CI 0.8–4.3), but negatively associated with lateral tibial cartilage volume (B = −4.9, 95%CI −8.4 to −1.5). The association of APMM and time from APMM with patellar cartilage defects was independent of tibial cartilage volume.
Partial medial meniscectomy is associated with adverse effects on articular cartilage and subchondral bone, which are associated with subsequent osteoarthritis, in both tibiofemoral and patellofemoral compartments.
Level of evidence
KeywordsMeniscectomy Cartilage Subchondral bone Magnetic resonance imaging Osteoarthritis
- 5.Bolano LE, Grana WA (1993) Isolated arthroscopic partial meniscectomy. Functional radiographic evaluation at five years. Am J Sports Med 21(3):432–437Google Scholar
- 10.Conaghan PG, Felson D, Gold G, Lohmander S, Totterman S, Altman R (2006) MRI and non-cartilaginous structures in knee osteoarthritis. Osteoarthr Cartil 14(Suppl A):A87–A94Google Scholar
- 15.Eckstein F, Cicuttini F, Raynauld JP, Waterton JC, Peterfy C (2006) Magnetic resonance imaging (MRI) of articular cartilage in knee osteoarthritis (OA): morphological assessment. Osteoarthr Cartil 14(Suppl A):A46–A75Google Scholar
- 27.Maletius W, Messner K (1996) The effect of partial meniscectomy on the long-term prognosis of knees with localized, severe chondral damage. A twelve- to fifteen-year followup. Am J Sports Med 24(3):258–262Google Scholar
- 31.Petersen MM, Olsen C, Lauritzen JB, Lund B, Hede A (1996) Late changes in bone mineral density of the proximal tibia following total or partial medial meniscectomy. A randomized study. J Orthop Res 14(1):16–21Google Scholar
- 32.Radin EL, Burr DB, Caterson B, Fyhrie D, Brown TD, Boyd RD (1991) Mechanical determinants of osteoarthrosis. Semin Arthritis Rheum 21(3 Suppl 2):12–21Google Scholar
- 35.Rockborn P, Gillquist J (1996) Long-term results after arthroscopic meniscectomy. The role of preexisting cartilage fibrillation in a 13 year follow-up of 60 patients. Int J Sports Med 17(8):608–613Google Scholar
- 45.Wolski M, Stachowiak GW, Dempsey AR, Mills PM, Cicuttini FM, Wang YY, Stoffel KK, Lloyd DG, Podsiadlo P (2011) Trabecular bone texture detected by plain radiography and variance orientation transform method is different between knees with and without cartilage defects. J Orthop Res 29(8):1161–1167PubMedCrossRefGoogle Scholar