Knee Surgery, Sports Traumatology, Arthroscopy

, Volume 18, Issue 2, pp 181–186 | Cite as

Prophylactic use of antibiotic-loaded bone cement in primary total knee replacement

  • Pietro RandelliEmail author
  • Francesco R. Evola
  • Paolo Cabitza
  • Luca Polli
  • Matteo Denti
  • Luca Vaienti


Despite significant advances in intraoperative antimicrobial procedures, deep infection remains the most devastating complication following total joint arthroplasty. Clinical studies’ results and safety profile of antibiotic-loaded bone cement are discussed in this review. Antibiotic bone cement prophylaxis is a safe and effective strategy in reducing the risk of deep infection following primary total joint arthroplasty.


Infection Total knee arthroplasty Antibiotic-loaded cement 


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Pietro Randelli
    • 1
    Email author
  • Francesco R. Evola
    • 2
  • Paolo Cabitza
    • 1
  • Luca Polli
    • 1
  • Matteo Denti
    • 3
  • Luca Vaienti
    • 1
  1. 1.Dipartimento di Scienze Medico-ChirurgicheUniversità degli Studi di Milano, Policlinico San Donato IRCCSMilanItaly
  2. 2.Clinica Ortopedica, Dipertimento di Specialità Medico-ChirurgicheUniversità degli Studi di Catania, Ospedale Vittorio Emanuele IICataniaItaly
  3. 3.Centro di Traumatologia dello SportIstituto Ortopedico GaleazziMilanItaly

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