Intensive Care Medicine

, Volume 45, Issue 2, pp 292–294 | Cite as

Effect of body position and inclination in supine and prone position on respiratory mechanics in acute respiratory distress syndrome

  • Mehdi Mezidi
  • Claude GuérinEmail author


The mechanism by which prone position (PP) reduces mortality in moderate-to-severe acute respiratory distress syndrome (ARDS) patients as compared to supine (SP) [1] likely includes reduction/homogenization of lung stress/strain. The common accepted scenario is that this effect stems from an increase in chest wall elastance (Est,cw) in PP. However, whether, and to what extent, the angulation of the body may affect Est,cw is unclear. Our hypothesis is that thorax inclination significantly changes respiratory system mechanics and lung volume from SP to PP, as previously suggested in healthy humans [2] and anesthetized patients [3].


The present report is an ancillary study of a previous published work [4]. In ARDS patients receiving continuous infusion of sedative and neuromuscular blockade agents, lung and chest wall mechanics, end-expiratory lung volume (EELV), and transcutaneous oxygen saturation (SpO2) were measured in the following order: SP 30° head-up (SP30°),...


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Conflicts of interest

The authors declare no conflict of interest.

Supplementary material

134_2018_5493_MOESM1_ESM.docx (193 kb)
Supplementary material 1 (DOCX 193 KB)


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Service de Médecine Intensive-RéanimationHôpital de La Croix-Rousse, Hospices civils de LyonLyonFrance
  2. 2.Université de LyonLyonFrance
  3. 3.INSERM 955CréteilFrance
  4. 4.Service de Médecine Intensive-RéanimationGrenobleFrance
  5. 5.HP2 INSERM 1042GrenobleFrance

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