Intensive Care Medicine

, Volume 43, Issue 11, pp 1732–1734 | Cite as

The effect of high-dose cholecalciferol on bioavailable vitamin D levels in critically ill patients: a post hoc analysis of the VITdAL-ICU trial

  • Gennaro Martucci
  • Fabio Tuzzolino
  • Antonio Arcadipane
  • Thomas R. Pieber
  • Christian Schnedl
  • Tadeja Urbanic Purkart
  • Gerlies Treiber
  • Karin Amrein
Letter
  • 705 Downloads

Supplementary material

134_2017_4846_MOESM1_ESM.doc (74 kb)
Supplementary material 1 (DOC 74 kb)

References

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    Amrein K, Christopher KB, McNally JD (2015) Understanding vitamin D deficiency in intensive care patients. Intensive Care Med 41:1961–1964CrossRefPubMedGoogle Scholar
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    McNally JD, Ginde AA, Amrein K (2017) Clarification needed for the systematic review of vitamin D trials in the ICU. Intensive Care Med 43(4):595–596CrossRefPubMedGoogle Scholar
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    Quraishi SA, De Pascale G, Needleman JS, Nakazawa H, Kaneki M, Bajwa EK, Camargo CA Jr, Bhan I (2015) Effect of cholecalciferol supplementation on vitamin D status and cathelicidin levels in sepsis: a randomized, placebo-controlled trial. Crit Care Med 43:1928–1937CrossRefPubMedPubMedCentralGoogle Scholar
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    Nielson CM, Jones KS, Bouillon R, Chun RF, Jacobs J, Wang Y, Hewison M, Adams JS, Swanson CM, Lee CG, Vanderschueren D, Pauwels S, Prentice A, Smith RD, Shi T, Gao Y, Zmuda JM, Lapidus J, Cauley JA, Schoenmakers I, Orwoll ES (2016) Role of assay type in determining free 25-hydroxyvitamin D levels in diverse populations. N Engl J Med 374:1695–1696CrossRefPubMedPubMedCentralGoogle Scholar
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    Amrein K, Schnedl C, Holl A, Riedl R, Christopher KB, Pachler C, Urbanic Purkart T, Waltensdorfer A, Munch A, Warnkross H, Stojakovic T, Bisping E, Toller W, Smolle KH, Berghold A, Pieber TR, Dobnig H (2014) Effect of high-dose vitamin D3 on hospital length of stay in critically ill patients with vitamin D deficiency: the VITdAL-ICU randomized clinical trial. JAMA 312:1520–1530CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg and ESICM 2017

Authors and Affiliations

  • Gennaro Martucci
    • 1
  • Fabio Tuzzolino
    • 2
  • Antonio Arcadipane
    • 1
  • Thomas R. Pieber
    • 3
  • Christian Schnedl
    • 4
  • Tadeja Urbanic Purkart
    • 5
  • Gerlies Treiber
    • 3
  • Karin Amrein
    • 3
  1. 1.Department of Anesthesia and Intensive CareIRCCS-ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad Alzta Specializzazione) PalermoPalermoItaly
  2. 2.Research OfficeIRCCS-ISMETT, (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione) PalermoPalermoItaly
  3. 3.Division of Endocrinology and Diabetology, Department of Internal MedicineMedical University of GrazGrazAustria
  4. 4.Institute of Diagnostic and Interventional RadiologyKlinikum Klagenfurt am WoertherseeKlagenfurtAustria
  5. 5.Division of General Neurology, Department of NeurologyMedical University of GrazGrazAustria

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