Intensive Care Medicine

, Volume 43, Issue 3, pp 465–467 | Cite as

High-flow oxygen via tracheostomy improves oxygenation in patients weaning from mechanical ventilation: a randomised crossover study

  • Amanda CorleyEmail author
  • Melannie Edwards
  • Amy J. Spooner
  • Kimble R. Dunster
  • Chris Anstey
  • John F. Fraser

Weaning tracheostomised patients from prolonged mechanical ventilation (PMV) is challenging and at great financial cost. PMV is associated with significant morbidity and mortality which increases with the period of mechanical ventilation [1]. Moreover, patients receiving PMV account for 6% of all ventilated patients but consume 37% of intensive care unit (ICU) resources [2].

High-flow nasal cannulae (HFNC) have demonstrated clinical benefits; however, these effects may not translate to high-flow tracheal oxygen (HFT) as mechanisms of action may differ between the two delivery modes. Limited evidence guides HFT use in clinical practice. Therefore, we undertook a randomised crossover study examining HFT’s effects on lung volumes [end-expiratory lung volume (EELV), tidal volume], airway pressure (Paw), oxygenation (SpO2/FiO2 ratio), ventilation [end-tidal carbon dioxide (etCO2)], respiratory rate (RR), heart rate and subjective dyspnoea compared with low-flow oxygen [T-piece (TP)].



Lung Volume Supplementary Material Table Prolonged Mechanical Ventilation Intensive Care Unit Length Randomise Crossover Study 
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This work was supported by a competitive grant from The Prince Charles Hospital Foundation Experienced Researcher grant. JFF would like to acknowledge his research fellowship from Queensland Health Office of Health and Medical Research.

Compliance with ethical standards

Conflicts of interest

JFF and AC have received assistance from Fisher and Paykel Healthcare Ltd to support travel and accommodation costs to attend research meetings. Fisher and Paykel Healthcare Ltd had no part in the current study. Other authors declare they have no conflicts of interest.

Supplementary material

134_2016_4634_MOESM1_ESM.doc (32 kb)
Supplementary material 1 (DOC 32 kb)
134_2016_4634_MOESM2_ESM.doc (118 kb)
Supplementary material 2 (DOC 117 kb)
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Supplementary material 3 (DOC 126 kb)
134_2016_4634_MOESM4_ESM.doc (38 kb)
Supplementary material 4 (DOC 38 kb)
134_2016_4634_MOESM5_ESM.doc (136 kb)
Supplementary material 5 (DOC 136 kb)


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Copyright information

© Springer-Verlag Berlin Heidelberg and ESICM 2016

Authors and Affiliations

  • Amanda Corley
    • 1
    Email author
  • Melannie Edwards
    • 1
  • Amy J. Spooner
    • 1
  • Kimble R. Dunster
    • 1
  • Chris Anstey
    • 1
    • 2
  • John F. Fraser
    • 1
  1. 1.Critical Care Research GroupThe Prince Charles Hospital and University of QueenslandChermsideAustralia
  2. 2.Intensive Care UnitNambour HospitalNambourAustralia

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