Intensive Care Medicine

, Volume 43, Issue 2, pp 277–278 | Cite as

Randomised trials of vitamin D3 for critically ill patients in adults: systematic review and meta-analysis with trial sequential analysis

  • Hong Weng
  • Jian-Guo Li
  • Zhi Mao
  • Xian-Tao ZengEmail author


Mean Difference Intensive Care Unit Stay Relative Risk Reduction Bias Assessment Comprehensive Literature Search 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Compliance with ethical standards

Conflicts of interest

The authors declare to have no possible conflict of interest.

Supplementary material

134_2016_4591_MOESM1_ESM.docx (435 kb)
Supplementary material 1 (DOCX 434 kb)


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    Zhang YP, Wan YD, Sun TW et al (2014) Association between vitamin D deficiency and mortality in critically ill adult patients: a meta-analysis of cohort studies. Crit Care 18:684CrossRefPubMedPubMedCentralGoogle Scholar
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    de Haan K, Groeneveld AB, de Geus HR et al (2014) Vitamin D deficiency as a risk factor for infection, sepsis and mortality in the critically ill: systematic review and meta-analysis. Crit Care 18:660CrossRefPubMedPubMedCentralGoogle Scholar
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    Michael A, Vera ADP (2012) Effect of vitamin D deficiency in critically ill patients. Am Thorac Soc, pp. A2556Google Scholar
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    Martin-Loeches I, Perner A (2016) Focus on infection and sepsis in intensive care patients. Intensive Care Med 42:491–493CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg and ESICM 2016

Authors and Affiliations

  • Hong Weng
    • 1
  • Jian-Guo Li
    • 2
  • Zhi Mao
    • 3
  • Xian-Tao Zeng
    • 1
    Email author
  1. 1.Center of Evidence Based and Translational MedicineZhongnan Hospital of Wuhan UniversityWuhanChina
  2. 2.Department of Critical Care MedicineZhongnan Hospital of Wuhan UniversityWuhanChina
  3. 3.Department of Critical Care MedicineChinese PLA General HospitalBeijingChina

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