Understanding preoxygenation and apneic oxygenation during intubation in the critically ill
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The most common adverse event encountered during the intubation of critically ill patients is oxygen desaturation, which is often a harbinger of serious complications such as cardiovascular collapse, anoxic brain injury, and death. It is imperative to attenuate this risk by optimizing preoxygenation prior to intubation. This paper explores the physiology and challenges related to preoxygenation and maintenance of oxygenation during intubation in these high-risk patients.
KeywordsFeO2 Functional Residual Capacity Nasal Cannula Alveolar Recruitment Shunt Fraction
Compliance with ethical standards
Conflicts of interest
None for all authors.
- 2.Hayes-Bradley C, Lewis A, Burns B et al (2015) Efficacy of nasal cannula oxygen as a preoxygenation adjunct in emergency airway management. Ann Emer Med. doi: 10.1016/j.annemergmed.2015.11.012
- 5.Papazian L, Corley A, Hess D et al (2016) Use of high-flow nasal cannula oxygenation in ICU adults: a narrative review. Intensive Care Med. doi: 10.1007/s00134-016-4277-8
- 9.Sakles JC, Mosier J, Patanwala AE et al (2016) First pass success without hypoxemia is increased with the use of apneic oxygenation during RSI in the emergency department. Acad Emer Med 23(6):703–10Google Scholar
- 14.Besnier E, Guernon K, Bubenheim M et al (2016) Pre-oxygenation with high-flow nasal cannula oxygen therapy and non-invasive ventilation for intubation in the intensive care unit. Intensive Care Med. doi: 10.1007/s00134-016-4369-5