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Intensive Care Medicine

, Volume 43, Issue 2, pp 226–228 | Cite as

Understanding preoxygenation and apneic oxygenation during intubation in the critically ill

  • Jarrod M. MosierEmail author
  • Cameron D. Hypes
  • John C. Sakles
Understanding the Disease

The most common adverse event encountered during the intubation of critically ill patients is oxygen desaturation, which is often a harbinger of serious complications such as cardiovascular collapse, anoxic brain injury, and death. It is imperative to attenuate this risk by optimizing preoxygenation prior to intubation. This paper explores the physiology and challenges related to preoxygenation and maintenance of oxygenation during intubation in these high-risk patients.

The purpose of preoxygenation is to maintain hemoglobin saturation despite ongoing oxygen consumption during apnea. This is accomplished in principle by denitrogenating the alveoli so that the functional residual capacity (FRC) serves as an oxygen reservoir, the efficacy of which can be evaluated by the fraction of expired O 2 (FeO 2) (Fig.  1).

Keywords

FeO2 Functional Residual Capacity Nasal Cannula Alveolar Recruitment Shunt Fraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Compliance with ethical standards

Conflicts of interest

None for all authors.

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Copyright information

© Springer-Verlag Berlin Heidelberg and ESICM 2016

Authors and Affiliations

  • Jarrod M. Mosier
    • 1
    • 2
    Email author
  • Cameron D. Hypes
    • 1
    • 2
  • John C. Sakles
    • 2
  1. 1.Section of Pulmonary, Critical Care, Allergy and Sleep, Department of MedicineUniversity of ArizonaTucsonUSA
  2. 2.Department of Emergency MedicineUniversity of ArizonaTucsonUSA

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