Critical care transition programs and the risk of readmission or death after discharge from ICU
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Critical care transition programs have been widely implemented to improve the safety of patient discharge from ICU, but have undergone limited evaluation. We sought to evaluate implementation of a critical care transition program on patient readmission to ICU (72 h) and mortality (14 days).
Interrupted time series analysis of 32,234 consecutive adult patients discharged alive from medical-surgical ICUs in eight hospitals in two cities between January 1, 2002 and January 1, 2012. A multidisciplinary ICU provider team (physician, nurse, respiratory therapist) that serially evaluated each patient after ICU discharge was implemented in three hospitals in one city (study group), but not the five hospitals in the other city (control group). Temporal changes were examined using multivariable, segmented linear regression models.
After implementation of the program, there was an immediate non-significant decrease in the absolute proportion of patients readmitted to ICU in the study group (−0.4 %, 95 % CI −1.7 to +1.0 %) and a non-significant increase in the absolute proportion of patients readmitted to ICU in the control group (+1.0 %, 95 % CI −0.3 to +2.2 %). Subsequently, there were non-significant changes in the absolute proportion of patients readmitted to ICU in both the study (+0.1 % per quarter; 95 % CI, −0.1 to +0.2 %) and control (−0.1 per quarter; 95 % CI, −0.2 to +0.1 %) groups over time. No significant changes were observed in mortality. The results were stable across patient subgroups.
Implementation of a critical care transition program was not associated with patient readmission to ICU or mortality.
KeywordsIntensive care unit Patient discharge Mortality Readmission Patient handoff
The study was funded by an establishment grant from Alberta Innovates—Health Solutions (20,100,368). HTS is supported by a Population Health Investigator Award from Alberta Innovates—Health Solutions. DJN is supported by a Clinician Fellowship Award from Alberta Innovates—Health Solutions, and a Knowledge Translation Canada Student Fellowship and Training Program grant. SMB is supported by a Canada Research Chair in Critical Care Nephrology and Clinical Investigator Award from Alberta Innovates—Health Solutions. Funding sources had no role in the design, conduct, or reporting of this study and we are unaware of any conflicts of interest. Dr Stelfox and Mr Gao had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Compliance with ethical standards
Conflicts of interest
Funding sources had no role in the design, conduct, or reporting of this study and we are unaware of any conflicts of interest.
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