Intensive Care Medicine

, Volume 42, Issue 5, pp 951–952 | Cite as

Effects of extracorporeal carbon dioxide removal on work of breathing in patients with chronic obstructive pulmonary disease

  • Jean-Luc Diehl
  • Lise Piquilloud
  • Jean-Christophe M. Richard
  • Jordi Mancebo
  • Alain Mercat


Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease Patient Respiratory Muscle Adult Respiratory Distress Syndrome Exacerbate Chronic Obstructive Pulmonary Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Compliance with ethical standards

Conflicts of interest

Jean-Luc Diehl has acted as a consultant for Alung Technologies and Xenios-Novalung. Funding for research purposes: Alung Technologies (EPHEBE study, NCT02586948). Jean-Christophe Richard is currently an employee from Air Liquide Medical Systems. The other authors have no conflict of interest in relation to the subject of the letter to declare.


  1. 1.
    Sklar MC, Beloncle F, Katsios CM et al (2015) Extracorporeal carbon dioxide removal in patients with chronic obstructive pulmonary disease: a systematic review. Intensive Care Med 41:1752–1762. doi: 10.1007/s00134-015-3921-z CrossRefPubMedGoogle Scholar
  2. 2.
    Diehl JL (2015) Physiological study of minimally invasive ECCO2R in exacerbations of COPD requiring invasive mechanical ventilation (EPHEBE). Accessed 2 Feb 2016
  3. 3.
    Diehl JL, Mercat A, Guerot E et al (2003) Helium/oxygen mixture reduces the work of breathing at the end of the weaning process in patients with severe chronic obstructive pulmonary disease. Crit Care Med 31:1415–1420CrossRefPubMedGoogle Scholar
  4. 4.
    Pisani L, Fasano L, Corcione N et al (2015) Effects of extracorporeal CO2 removal on inspiratory effort and respiratory pattern in patients who fail weaning from mechanical ventilation. Am J Respir Crit Care Med 192:1392–1394Google Scholar
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    Robergs RA, Ghiasvand F, Parker D (2004) Biochemistry of exercise-induced metabolic acidosis. Am J Physiol Regul Integr Comp Physiol 287:R502–R516CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg and ESICM 2016

Authors and Affiliations

  • Jean-Luc Diehl
    • 1
    • 2
  • Lise Piquilloud
    • 3
    • 4
  • Jean-Christophe M. Richard
    • 5
  • Jordi Mancebo
    • 6
  • Alain Mercat
    • 3
  1. 1.Service de Réanimation MédicaleHôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de ParisParisFrance
  2. 2.Faculté des Sciences Pharmaceutiques et Biologiques 4 av. de l’ObservatoireINSERM UMR_S1140: Innovations Thérapeutiques en Hémostase; Université Paris DescartesParis Cedex 06France
  3. 3.Medical Intensive Care UnitUniversity Hospital of AngersAngersFrance
  4. 4.Adult Intensive Care and Burn UnitUniversity Hospital of LausanneLausanneSwitzerland
  5. 5.Annecy HospitalAnnecyFrance
  6. 6.Servei de Medicina IntensivaHospital de Sant PauBarcelonaSpain

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