Long-term survival after extracorporeal life support in children with neutropenic sepsis
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Extracorporeal life support (ECLS) is an established intervention for paediatric patients with cardiorespiratory failure failing conventional therapy. Malignancy was historically regarded as a contraindication to ECLS, but analyses of the Extracorporeal Life Support Organization registry demonstrated that ECLS could be appropriate in carefully selected patients [1, 2]. Neutropenic sepsis that complicates chemotherapy has also been regarded as a contraindication to ECLS because of the uncertain long-term prognosis and vulnerability of these children to nosocomial infection. However, there are minimal data on the use of ECLS for this indication. We reviewed our institutional experience of children with febrile neutropenia receiving ECLS.
The study was approved by the institutional review board and waiver of informed consent was granted. A retrospective chart review was conducted on all paediatric patients with known malignancy commenced on ECLS at the Royal Children’s...
KeywordsHospital Discharge Renal Replacement Therapy Febrile Neutropenia Continuous Renal Replacement Therapy Neutropenic Patient
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Conflicts of interest
On behalf of all authors, the corresponding author states that there is no conflict of interest.