Management of necrotizing soft tissue infections in the intensive care unit: results of an international survey
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Necrotizing soft tissue infections (NSTIs) are rare and life-threatening bacterial infections characterized by subcutaneous tissue, fascia, or muscle necrosis. The mortality of NSTIs is high, ranging from 20 % in non-selected patients to up to 50 % in the most severe forms requiring intensive care unit (ICU) admission [1, 2]. Early recognition of NSTI is crucial; however, its management is challenging and requires a coordinated and multidisciplinary approach. Treatment of NSTIs consists of early broad-spectrum antimicrobial therapy together with emergency and aggressive surgical debridement with excision of all necrotic and infected tissues . We aimed to assess the burden of NSTIs and the organization of their early management in ICUs worldwide.
KeywordsClindamycin Soft Tissue Infection Intensive Care Medicine Surgical Debridement Recent Guideline
The authors thank the European Society of Intensive Care Medicine (ESICM) for endorsing this survey, particularly Guy François for organizational aspects and Profs Jacques Duranteau (Research Committee) and Jan De Waele (Infection Section) for reviewing the questionnaire.
Henri Mondor Hospital Necrotizing Fasciitis Group
Roland Amathieu, Romain Bosc, Christian Brun-Buisson, Olivier Chosidow, Jean-Winoc Decousser, Gilles DHonneur, Marine Desroches, Camille Hua, Raphael Lepeule, Nicolas de Prost, Alain Rahmouni, Emilie Sbidian.
Compliance with ethical standards
Conflicts of interest
The authors have no conflict of interest.
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