Pneumocystis jirovecii airborne transmission between critically ill patients and health care workers
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Airborne transmission of Pneumocystis between immunocompromised and immunocompetent hosts has been demonstrated in animal models . In humans, colonization with P. jirovecii has been identified in immunocompromised and immunocompetent individuals . The role of colonized people is still unclear, but a recent study provided arguments for colonized patients to be potential sources of nosocomial acquisition of Pneumocystis .
This prospective study was conducted between January and October 2012 to assess the implication of Pneumocystis-colonized subjects in Pneumocystis transmission (study design described in Supplementary Figure). Health care workers (HCW) were defined as “contact” if they stayed more than 5 min and less than 2 m from an infected patient. P. jirovecii DNA was detected by nasal swab and/or oropharyngeal wash as previously described . Air samples were performed by using a liquid cyclone-style air sampling device (Coriolis µ®, Bertin) as previously...
KeywordsInternal Transcribe Space Health Care Worker Nasal Swab Fungal Burden Pneumocystis Jirovecii
This work was supported in part by the Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail (grant nr. EST-2011/1/053) and by the Institut de Médecine et d’Epidémiologie Appliquée.
Conflicts of interest
The authors report no conflicts of interest.