Intensive Care Medicine

, Volume 41, Issue 5, pp 895–898 | Cite as

Laboratory diagnosis of Ebola virus disease

  • Philippe Martin
  • Kevin B. Laupland
  • Eric H. Frost
  • Louis ValiquetteEmail author
What's New in Intensive Care


An outbreak of Ebola virus disease (EVD) began in Guinea in December 2013, and by 21 November 2014, 15,531 cases had been identified with 5,429 associated deaths primarily in Guinea, Liberia, and Sierra Leone [1, 2]. Case fatality rates during the current outbreak are around 70 % among patients with known outcome [1]. As treatment options are limited and largely supportive, preventative measures are paramount in the control of this disease. Rapid and reliable diagnosis of EVD is critically important for patient management, infection prevention, and control measures, and optimization of use of healthcare resources. This article briefly reviews new developments in the diagnosis of EVD.

General considerations

Although a presumptive diagnosis of EVD may be made in the appropriate clinical context based on exposure history, symptoms, signs, and findings on routine laboratory evaluation, confirmation using specific tests is required [3, 4]. Clinically EVD may be confused with...


Typhoid Fever Antigen Detection Personal Protective Equipment Polymerase Chain Reaction Technique Rapid Antigen Detection Test 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Conflicts of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.


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Copyright information

© Springer-Verlag Berlin Heidelberg and ESICM 2015

Authors and Affiliations

  • Philippe Martin
    • 1
  • Kevin B. Laupland
    • 2
    • 3
  • Eric H. Frost
    • 1
  • Louis Valiquette
    • 1
    Email author
  1. 1.Department of Microbiology and Infectious DiseasesUniversité de SherbrookeSherbrookeCanada
  2. 2.Department of MedicineRoyal Inland HospitalKamloopsCanada
  3. 3.Departments of Medicine, Critical Care Medicine, Pathology and Laboratory Medicine and Community Health SciencesUniversity of CalgaryCalgaryCanada

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