Intensive Care Medicine

, Volume 41, Issue 3, pp 511–513 | Cite as

Isolation in patients with Ebola virus disease

  • Dominic WichmannEmail author
  • Stefan Schmiedel
  • Stefan Kluge
What's New in Intensive Care


Ebola filoviruses are the causative pathogens of a severe form of viral haemorrhagic fever with high case fatality rates in humans (50–90 %; more than 70 % in the current outbreak), designated Ebola haemorrhagic fever or Ebola virus disease (EVD). Ebola is endemic in regions of Central and Western Africa [1, 2].

Currently, beginning in late 2013, an unprecedented epidemic with several thousand cases and deaths (as per WHO report 05.11.2014: 13,042 documented cases, 4,818 deaths) is unfolding in Guinea, Liberia and Sierra Leone, and spreading to other countries in Africa, Europe and the USA where isolated cases have occurred [1, 3, 4, 5, 6].

Ebola transmission occurs exclusively through direct contact with body fluids through mucosal surfaces, skin abrasions, or by parenteral introduction—an aerosolised or droplet transmission has not so far been reported. Health care personal infections have not only happened after needle sticks but also after unsafe personal protection...


Haemorrhagic Fever Personal Protection Equipment Health Care Personnel Health Care Staff Haemorrhagic Fever Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Conflicts of interest

The authors do not have a conflict of interests.

Supplementary material

134_2014_3582_MOESM1_ESM.docx (76 kb)
Supplementary material 1 (DOCX 76 kb). List of basic requirements for PPE

Supplementary material 2 (M4V 260679 kb). Donning, decontamination and doffing when using positive-pressure-suits

Supplementary material 3 (Mp4 63081 kb). Donning, decontamination and doffing when using positive-pressure-suits. (Low-resolution video)


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Copyright information

© Springer-Verlag Berlin Heidelberg and ESICM 2014

Authors and Affiliations

  • Dominic Wichmann
    • 1
    Email author
  • Stefan Schmiedel
    • 2
  • Stefan Kluge
    • 1
  1. 1.Department of Intensive Care MedicineUniversity Medical Center Hamburg-EppendorfHamburgGermany
  2. 2.Infectious Disease and Tropical Medicine, Department of Medicine IUniversity Medical Center Hamburg-EppendorfHamburgGermany

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