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Intensive Care Medicine

, Volume 40, Issue 6, pp 920–921 | Cite as

Hypertonic lactate and the injured brain: facts and the potential for positive clinical implications

  • Pierre BouzatEmail author
  • Pierre J. Magistretti
  • Mauro Oddo
Correspondence

Keywords

Traumatic Brain Injury Intracranial Hypertension Cerebral Damage Cerebral Microdialysis Lactate Oxidation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Conflicts of interest

None to declare.

References

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    Sala N, Suys T, Zerlauth JB, Bouzat P, Messerer M, Bloch J, Levivier M, Magistretti PJ, Meuli R, Oddo M (2013) Cerebral extracellular lactate increase is predominantly nonischemic in patients with severe traumatic brain injury. J Cereb Blood Flow Metab 33:1815–1822PubMedCrossRefGoogle Scholar
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    Bouzat P, Sala N, Suys T, Zerlauth JB, Marques-Vidal P, Feihl F, Bloch J, Messerer M, Levivier M, Meuli R, Magistretti PJ, Oddo M (2014) Cerebral metabolic effects of exogenous lactate supplementation on the injured human brain. Intensive Care Med 40:412–421. doi: 10.1007/s00134-013-3203-6 PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg and ESICM 2014

Authors and Affiliations

  • Pierre Bouzat
    • 1
    • 2
    Email author
  • Pierre J. Magistretti
    • 3
    • 4
  • Mauro Oddo
    • 1
  1. 1.Neuroscience Critical Care Research Unit, Department of Intensive Care Medicine, Centre Hospitalier Universitaire Vaudois (CHUV)University Hospital and Faculty of Biology and MedicineLausanneSwitzerland
  2. 2.Joseph Fourier UniversityGrenobleFrance
  3. 3.Laboratory of Neuroenergetics and Cellular Dynamics, Centre de Neurosciences Psychiatriques (CHUV), Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL)University Hospital and Faculty of Biology and MedicineLausanneSwitzerland
  4. 4.BESE DivisionKAUSTThuwalSaudi Arabia

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