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Intensive Care Medicine

, Volume 36, Issue 7, pp 1256–1260 | Cite as

Effect of the AutoPulse™ automated band chest compression device on hemodynamics in out-of-hospital cardiac arrest resuscitation

  • François-Xavier DuchateauEmail author
  • Papa Gueye
  • Sonja Curac
  • Florence Tubach
  • Claire Broche
  • Patrick Plaisance
  • Didier Payen
  • Jean Mantz
  • Agnès Ricard-Hibon
Brief Report

Abstract

Purpose

Guidelines for advanced life support of cardiac arrest (CA) emphasize continuous and effective chest compressions as one of the main factors of cardiopulmonary resuscitation (CPR) success. The use of an automated load distributing chest compression device for CPR is promising but initial studies on survival show contradictory results. The aim of this study was to evaluate the effects of AutoPulse™ on blood pressure (BP) in out-of-hospital CA patients.

Methods

This prospective study included adult patients presenting with in refractory out-of-hospital CA. Invasive arterial BP produced by AutoPulse™ was compared to BP generated by manual CPR (Active Compression Decompression). Systolic, diastolic and mean BP and end-tidal carbon dioxide were recorded before and after initiating the automated band device for each patient. The comparison of diastolic BP produced by manual CPR versus automated chest compressions was the primary end point.

Results

Hemodynamics in 29 patients are reported and analyzed. Median diastolic BP increased after starting AutoPulse™ from 17[11–25] mmHg to 23[18–28] mmHg (P < 0.001). Median systolic BP increased from 72[55–105] mmHg to 106[78–135] mmHg (P = 0.02). Mean BP increased from 29[25–38] mmHg to 36[30–15] mmHg (P = 0.002). On the other hand, End-Tidal CO2 did not increase significantly with AutoPulse™ (21[13–36] vs. 22[12–35] mmHg, P = 0.80).

Conclusions

In patients with out-of-hospital CA, the use of AutoPulse™ is associated with an increased diastolic BP compared to manual chest compressions. While its benefit to survival has yet to be demonstrated, the increase in diastolic and mean BP is a promising outcome for AutoPulse™ use.

Keywords

Hemodynamics Cardiac arrest Resuscitation Out-of-hospital 

Notes

Acknowledgments

We would like to acknowledge Bernard Cholley, MD, PhD, for his technical help in interpreting the data and the French Society of Emergency Medicine fellowship for funding.

Conflict of interest statement

None of the authors has a potential conflict of interest.

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Copyright information

© Copyright jointly held by Springer and ESICM 2010

Authors and Affiliations

  • François-Xavier Duchateau
    • 1
    Email author
  • Papa Gueye
    • 2
  • Sonja Curac
    • 1
  • Florence Tubach
    • 4
  • Claire Broche
    • 2
  • Patrick Plaisance
    • 3
  • Didier Payen
    • 2
  • Jean Mantz
    • 1
  • Agnès Ricard-Hibon
    • 1
  1. 1.Department of Anaesthesiology and Intensive CareBeaujon University HospitalClichyFrance
  2. 2.Department of Anesthesiology and Critical CareLariboisiere University HospitalParisFrance
  3. 3.Emergency DepartmentLariboisiere University HospitalParisFrance
  4. 4.Clinical Research UnitBichat-Claude Bernard University HospitalParisFrance

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