Intensive Care Medicine

, 35:2028 | Cite as

Vitamin D deficiency in the intensive care unit: an invisible accomplice to morbidity and mortality?

  • Paul LeeEmail author
  • Priya Nair
  • John A. Eisman
  • Jacqueline R. Center
Clinical Perspective


The association between vitamin D deficiency and chronic illness is well-known. Vitamin D deficiency has been associated with increased mortality in the general population. Despite this knowledge, vitamin D insufficiency is seldom considered and rarely replaced adequately, if at all, in critically ill patients in intensive care. We present a hypothetic model demonstrating how vitamin D deficiency may be an unrecognized contributor to adverse outcome in intensive care patients.


Endocrine disorders Electrolyte disorders Multiple organ failure Nutrition Systemic diseases Cardiovascular issues in the ICU Vitamin D deficiency Hypocalcaemia 


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Copyright information

© Copyright jointly hold by Springer and ESICM 2009

Authors and Affiliations

  • Paul Lee
    • 1
    • 3
    • 5
    Email author
  • Priya Nair
    • 2
  • John A. Eisman
    • 1
    • 3
    • 4
    • 5
  • Jacqueline R. Center
    • 1
    • 3
    • 4
    • 5
  1. 1.Department of EndocrinologySt Vincent’s HospitalSydneyAustralia
  2. 2.Intensive Care UnitSt Vincent’s HospitalSydneyAustralia
  3. 3.Department of Endocrinology, Garvan Institute of Medical ResearchSydneyAustralia
  4. 4.Bone and Mineral Research ProgrammeGarvan Institute of Medical ResearchSydneyAustralia
  5. 5.University of New South WalesSydneyAustralia

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