Intensive Care Medicine

, Volume 35, Issue 2, pp 198–205 | Cite as

Interactions between respiration and systemic hemodynamics. Part II: practical implications in critical care

  • François FeihlEmail author
  • Alain F. Broccard


In Part I of this review, we have covered basic concepts regarding cardiorespiratory interactions. Here, we put this theoretical framework to practical use. We describe mechanisms underlying Kussmaul’s sign and pulsus paradoxus. We review the literature on the use of respiratory variations of blood pressure to evaluate volume status. We show the possibilities of attaining the latter aim by investigating with ultrasonography how the geometry of great veins fluctuates with respiration. We provide a Guytonian analysis of the effects of PEEP on cardiac output. We terminate with some remarks on the potential of positive pressure breathing to induce acute cor pulmonale, and on the cardiovascular mechanisms that at times may underly the failure to wean a patient from the ventilator.


Right Ventricular Continuous Positive Airway Pressure Superior Vena Cava Constrictive Pericarditis Pulmonary Artery Occlusion Pressure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



We warmly thank the reviewers for their contribution to this text, in the form of numerous thoughtful, in depth, and very constructive comments.


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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  1. 1.Division of Clinical PathophysiologyUniversity Hospital (CHUV) and Lausanne University (UNIL)LausanneSwitzerland
  2. 2.Medical Intensive Care Unit, Regions Hospital Pulmonary and Critical Care DivisionRegions HospitalSt PaulUSA
  3. 3.Division de Physiopathologie CliniqueLausanneSwitzerland

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