Intensive Care Medicine

, Volume 33, Issue 8, pp 1322–1328 | Cite as

Neuromonitoring in the intensive care unit. II. Cerebral oxygenation monitoring and microdialysis

  • Anuj Bhatia
  • Arun Kumar Gupta



Monitoring the injured brain is an integral part of the management of severely brain injured patients in intensive care. There is increasing interest in methods to monitor global and regional cerebral oxygenation. There have been significant advances in analysing tissue oxygenation and local metabolites in the injured brain over the past decade.


Cerebral oxygenation can be assessed on a global or regional basis by jugular venous oximetry and near infra-red spectroscopy respectively. Techniques of brain tissue oxygenation monitoring and microdialysis are also covered in this review.


Various modalities are available to monitor oxygenation and the local milieu in the injured brain in the intensive care unit. Use of these modalities helps to optimise brain oxygen delivery and metabolism in patients with acute brain injury.


Traumatic brain injury Oximetry, jugular venous Spectroscopy, near-infrared Microdialysis 



arteriovenous oxygen content difference


cerebral blood flow


cerebral metabolic rate of oxygen


cerebral perfusion pressure


computerised tomography


cytochrome aa3




γ-amino-butyric acid


haemoglobin (deoxygenated)


haemoglobin (oxygenated)


intracranial pressure


near-infrared spectroscopy


brain tissue oxygen partial pressure


brain tissue carbon dioxide partial pressure


positron emission tomography


subarachnoid haemorrhage


jugular venous oxygen saturation


traumatic brain injury


transcranial Doppler


tissue oxygenation index


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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  1. 1.Department of AnaesthesiaAddenbrooke’s HospitalCambridgeUK
  2. 2.Neuroscience Critical Care UnitAddenbrooke’s HospitalCambridgeUK

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