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Intensive Care Medicine

, Volume 33, Issue 1, pp 49–57 | Cite as

Year in review in Intensive Care Medicine, 2006. I. Experimental studies. Clinical studies: brain injury, renal failure and endocrinology

  • Peter Andrews
  • Elie Azoulay
  • Massimo Antonelli
  • Laurent BrochardEmail author
  • Christian Brun-Buisson
  • Daniel De Backer
  • Geoffrey Dobb
  • Jean-Yves Fagon
  • Herwig Gerlach
  • Johan Groeneveld
  • Duncan Macrae
  • Jordi Mancebo
  • Philipp Metnitz
  • Stefano Nava
  • Jerôme Pugin
  • Michael Pinsky
  • Peter Radermacher
  • Christian Richard
Year in Review 2006

Experimental studies

The “Experimental” studies, which were published both as original papers and in the form of brief communications, focused on three main subjects, i. e. improved techniques and side effects of mechanical ventilation, treatment of traumatic–hemorrhagic shock, and physiopathology and treatment of sepsis and septic shock.

Mechanical ventilation and lung injury

Experimental models of acute lung injury (ALI) have proved to be useful in achieving a better understanding of its pathogenesis and to test new ventilatory strategies. The type of lung injury model investigated, however, deeply influences the response to mechanical ventilation. In an interesting study, DiRocco et al. [1] investigated the alveolar mechanics in four different rat ALI models. ALI was induced by the detergent Tween-20, oleic acid, injurious mechanical ventilation, or endotoxin. Hypoxemia resulted in all four models. While significant alveolar instability was observed after Tween-20 and oleic acid...

Keywords

Traumatic Brain Injury Septic Shock Systemic Inflammatory Response Syndrome Intensive Care Unit Stay Septic Shock Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Peter Andrews
    • 1
  • Elie Azoulay
    • 2
  • Massimo Antonelli
    • 3
  • Laurent Brochard
    • 4
    Email author
  • Christian Brun-Buisson
    • 5
  • Daniel De Backer
    • 6
  • Geoffrey Dobb
    • 7
  • Jean-Yves Fagon
    • 8
  • Herwig Gerlach
    • 9
  • Johan Groeneveld
    • 10
  • Duncan Macrae
    • 11
  • Jordi Mancebo
    • 12
  • Philipp Metnitz
    • 13
  • Stefano Nava
    • 14
  • Jerôme Pugin
    • 15
  • Michael Pinsky
    • 16
  • Peter Radermacher
    • 17
  • Christian Richard
    • 18
  1. 1.Intensive Care Medicine UnitWestern General HospitalEdinburghUK
  2. 2.Intensive Care Medicine UnitSaint Louis HospitalParisFrance
  3. 3.Department of Intensive Care and AnesthesiologyUniversita Cattolica del Sacre CuoreRomeItaly
  4. 4.Réanimation Médicale, AP-HP, Hôpital Henri Mondor, INSERM U 651Université Paris 12CréteilFrance
  5. 5.Réanimation Médicale, AP-HP, Hôpital Henri MondorUniversité Paris 12CréteilFrance
  6. 6.Service des Soins IntensifsErasme HospitalBrusselsBelgium
  7. 7.Intensive Care Medicine UnitRoyal Perth HospitalPerthAustralia
  8. 8.Intensive Care Medicine UnitEuropean Georges Pompidou HospitalParisFrance
  9. 9.Department of AnesthesiologyVivantes-Klinikum NeukoellnBerlinGermany
  10. 10.Intensive Care Medicine UnitVUMCAmsterdamThe Netherlands
  11. 11.Pediatric Intensive Care UnitRoyal Brompton HospitalLondonUK
  12. 12.Intensive Care Medicine UnitHospital Sant PauBarcelonaSpain
  13. 13.Department of Anesthesia and General Intensive Care MedicineUniversity Hospital of ViennaViennaAustria
  14. 14.Intensive Care Medicine UnitFondazione S. MaugeriPaviaItaly
  15. 15.Intensive Care Medicine UnitUniversity Hospital of GenevaGenevaSwitzerland
  16. 16.Intensive Care Medicine UnitUniversity of Pittsburgh Medical CenterPittsburghUSA
  17. 17.Department of AnesthesiaUniversity Medical School of UlmUlmGermany
  18. 18.Intensive Care UnitUniversity Hospital of Le Kremlin-BicetreLe Kremlin-BicetreFrance

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