Defining and classifying acute renal failure: from advocacy to consensus and validation of the RIFLE criteria
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Until recently, more than 30 different definitions of acute renal failure (ARF) had been used in the literature. This lack of a common reference point created confusion and made comparisons difficult. It also led to strong advocacy of a consensus definition. In response to the need for a common definition and classification of ARF, the Acute Dialysis Quality Initiative (ADQI) group of experts developed and published a consensus definition of ARF. This definition goes under the acronym of RIFLE to indicate that it classifies patients with renal dysfunction according to the degree of impairment into patients at risk (R), with injury (I), with failure (F), with sustained loss (L) and with end-stage (E) status in relation to their renal function. This editorial aims to summarize and interpret recent findings concerning the application of the RIFLE criteria to the assessment of the epidemiology and the prediction of the outcome of ARF.
KeywordsAcute renal failure RIFLE definition Epidemiology Outcome Critical illness Cardiac surgery Hemodialysis Hemofiltration Kidney Illness severity
- 8.Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P, and the ADQI workgroup (2004) Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 8:R204–R210PubMedCrossRefGoogle Scholar
- 16.Lin C-Y, Chen Y-C, Tsai F-C, Tian Y-C, Jeng C-C, Fang J-T, Yang C-W (2006) RIFLE classification is predictive of short-term prognosis in critically ill patients with acute renal failure supported by extra-corporeal membrane oxygenation. Nephrol Dial Transplant July 24 [Epub ahead of print]Google Scholar
- 17.Lopes JA. Jorge S, Neves FC, Caneira M, Da Costa AG, Ferreira AC, Prata MM (2006) An assessment of the rifle criteria for acute renal failure in severely burned patients. Nephrol Dial Transplant July 31 [Epub ahead of print]Google Scholar
- 20.American College of Chest Physicians/Society of Critical Care Medicine Consensus Committee (1992) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 101:1658–1662Google Scholar