Advertisement

Intensive Care Medicine

, Volume 31, Issue 7, pp 911–913 | Cite as

Venous oximetry

  • Frank Bloos
  • Konrad ReinhartEmail author
Physiological Note

Introduction

The primary physiological task of the cardiovascular system is to deliver enough oxygen (O2) to meet the metabolic demands of the body. Shock and tissue hypoxia occur when the cardiorespiratory system is unable to cover metabolic demand adequately. Sustained tissue hypoxia is one of the most important cofactors in the pathophysiology of organ dysfunction [1]. Therefore determining the adequacy of tissue oxygenation in critically ill patients is central to ascertain the health of the patient. Unfortunately, normal values in blood pressure, central venous pressure, heart rate, and blood gases do not rule out tissue hypoxia or imbalances between whole-body oxygen supply and demand [2]. This discrepancy has led to increased interest in more direct indicators of adequacy of tissue oxygenation such as mixed and central venous oxygen saturations. Pulmonary artery catheterization allows obtaining true mixed venous oxygen saturation (SvO2) while measuring central venous oxygen...

Keywords

Septic Shock Inferior Vena Caval Pulmonary Artery Catheter Tissue Hypoxia CaO2 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Marshall JC (2001) Inflammation, coagulopathy, and the pathogenesis of multiple organ dysfunction syndrome. Crit Care Med 29:S99–S106CrossRefPubMedGoogle Scholar
  2. 2.
    Reinhart K (1989) Monitoring O2 transport and tissue oxygenation in critically ill patients. In: Reinhart K, Eyrich K (ed) Clinical aspects of O2 transport and tissue oxygenation. Springer, Berlin Heidelberg New York, pp 195–211Google Scholar
  3. 3.
    Reinhart K, Schäfer M, Rudolph T, Specht M (1989) Mixed venous oxygen saturation. Appl Cardiopulm Pathophysiol 2:315–325Google Scholar
  4. 4.
    Vincent JL, De Backer D (2004) Oxygen transport-the oxygen delivery controversy. Intensive Care Med 30:1990–1996CrossRefPubMedGoogle Scholar
  5. 5.
    Scheinman MM, Brown MA, Rapaport E (1969) Critical assessment of use of central venous oxygen saturation as a mirror of mixed venous oxygen in severely ill cardiac patients. Circulation 40:165–172PubMedGoogle Scholar
  6. 6.
    Lee J, Wright F, Barber R, Stanley L (1972) Central venous oxygen saturation in shock: a study in man. Anesthesiology 36:472–478PubMedGoogle Scholar
  7. 7.
    Reinhart K, Kuhn HJ, Hartog C, Bredle DL (2004) Continuous central venous and pulmonary artery oxygen saturation monitoring in the critically ill. Intensive Care Med 30:1572–1578CrossRefPubMedGoogle Scholar
  8. 8.
    Meier-Hellmann A, Specht M, Hannemann L, Hassel H, Bredle DL, Reinhart K (1996) Splanchnic blood flow is greater in septic shock treated with norepinephrine than in severe sepsis. Intensive Care Med 22:1354–1359CrossRefPubMedGoogle Scholar
  9. 9.
    Edwards JD, Mayall RM (1998) Importance of the sampling site for measurement of mixed venous oxygen saturation in shock. Crit Care Med 26:1356–1360CrossRefPubMedGoogle Scholar
  10. 10.
    Reinhart K, Rudolph T, Bredle DL, Hannemann L, Cain SM (1989) Comparison of central-venous to mixed-venous oxygen saturation during changes in oxygen supply/demand. Chest 95:1216–1221PubMedGoogle Scholar
  11. 11.
    Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345:1368–1377CrossRefPubMedGoogle Scholar
  12. 12.
    Rivers EP, Rady MY, Martin GB, Fenn NM, Smithline HA, Alexander ME, Nowak RM (1992) Venous hyperoxia after cardiac arrest. Characterization of a defect in systemic oxygen utilization. Chest 102:1787–1793PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  1. 1.Klinik für Anästhesiologie und IntensivtherapieKlinikum der Friedrich-Schiller-UniversitätJenaGermany

Personalised recommendations