Intensive Care Medicine

, Volume 32, Issue 3, pp 380–390 | Cite as

Year in review in intensive care medicine, 2005. II. Infection and sepsis, ventilator-associated pneumonia, ethics, haematology and haemostasis, ICU organisation and scoring, brain injury

  • Peter Andrews
  • Elie Azoulay
  • Massimo Antonelli
  • Laurent BrochardEmail author
  • Christian Brun-Buisson
  • Geoffrey Dobb
  • Jean-Yves Fagon
  • Herwig Gerlach
  • Johan Groeneveld
  • Jordi Mancebo
  • Philipp Metnitz
  • Stefano Nava
  • Jerome Pugin
  • Michael Pinsky
  • Peter Radermacher
  • Christian Richard
  • Robert Tasker
Year in Review 2005

Infection and sepsis

Prediction and outcome of infections

Because of their poor prognosis, patients with advanced haematological malignancies may be denied ICU admission. In a prospective cohort study of 172 patients with haematological malignancy admitted to a single ICU over a 4-year period, Benoit et al. [1] examined hospital and 6-month mortality after stratification on whether an infection was present, suspected or absent on ICU admission. After adjustment for the severity of critical and underlying haematological illness and the duration of hospitalisation before admission, documented ([odds ratio] OR 0.20; p = 0.006) and clinically suspected bacterial infection (OR 0.18; p = 0.002) were found associated with a more favourable outcome than nonbacterial complications leading to admission. The authors conclude that since the former have a better outcome, such patients should receive full supportive care for an adequate period of time.

Brivet et al. [2] analysed retrospectively 140...


Traumatic Brain Injury Sequential Organ Failure Assessment Emotional Exhaustion Sequential Organ Failure Assessment Score Simplified Acute Physiology Score 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Peter Andrews
    • 2
  • Elie Azoulay
    • 3
  • Massimo Antonelli
    • 4
  • Laurent Brochard
    • 1
    Email author
  • Christian Brun-Buisson
    • 1
  • Geoffrey Dobb
    • 5
  • Jean-Yves Fagon
    • 6
  • Herwig Gerlach
    • 7
  • Johan Groeneveld
    • 8
  • Jordi Mancebo
    • 9
  • Philipp Metnitz
    • 10
  • Stefano Nava
    • 11
  • Jerome Pugin
    • 16
  • Michael Pinsky
    • 12
  • Peter Radermacher
    • 13
  • Christian Richard
    • 14
  • Robert Tasker
    • 15
  1. 1.Réanimation MédicaleAP-HP, Hôpital Henri MondorParis 12France
  2. 2.Intensive Care UnitWestern General HospitalEdinburghUK
  3. 3.Intensive Care UnitSaint Louis HospitalParisFrance
  4. 4.Department of Intensive Cure and AnesthesiologyUniversita Cattolica del Sacro CuoreRomeItaly
  5. 5.Intensive Care UnitRoyal Perth HospitalPerth,Australia
  6. 6.Intensive Care UnitEuropean Georges Pompidou HospitalParisFrance
  7. 7.Department of AnesthesiologyVivantes-Klinikum NeukoellnBerlinGermany
  8. 8.Intensive Care UnitVUMCAmsterdamThe Netherlands
  9. 9.Intensive Care UnitHospital Sant PauBarcelonaSpain
  10. 10.Department of Anesthesia and General Intensive Care MedicineUniversity Hospital of ViennaViennaAustria
  11. 11.Intensive Care Medicine UnitFondazione S. MaugeriPaviaItaly
  12. 12.Intensive Care UnitUniversity of Pittsburgh Medical CenterPittsburghUSA
  13. 13.Department of AnesthesiaUniversity Medical School of UlmUlmGermany
  14. 14.Intensive Care UnitUniversity Hospital of Le Kremlin-BicetreLe Kremlin BicetreFrance
  15. 15.Pediatric Intensive Care UnitAddenbrook's HospitalCambridgeUK
  16. 16.Intensive Care UnitUniversity Hospital of GenevaGenevaSwitzerland

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