Intensive Care Medicine

, Volume 32, Issue 2, pp 207–216 | Cite as

Year in review in intensive care medicine. 2005. I. Acute respiratory failure and acute lung injury, ventilation, hemodynamics, education, renal failure

  • Peter Andrews
  • Elie Azoulay
  • Massimo Antonelli
  • Laurent BrochardEmail author
  • Christian Brun-Buisson
  • Daniel de Backer
  • Geoffrey Dobb
  • Jean-Yves Fagon
  • Herwig Gerlach
  • Johan Groeneveld
  • Jordi Mancebo
  • Philipp Metnitz
  • Stefano Nava
  • Jerome Pugin
  • Michael Pinsky
  • Peter Radermacher
  • Christian Richard
  • Robert Tasker
Year in Review 2005

Acute Respiratory Failure

Acute lung injury

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) have been the subjects of several important studies which address the issues of biological markers, respiratory monitoring tools to guide ventilatory settings, and risk factors for developing ARDS.

Fibroproliferation in ARDS seems to have important prognostic implications. Because fibroproliferation markers, such as procollagen I, predict mortality in patients with ALI and ARDS, Budinger et al. examined whether bronchoalveolar lavage fluid (BALF) from patients with lung injury contains mediators that would activate procollagen-I promoter, and if this activation predicts important clinical outcomes [1]. The BALF was also collected from patients with pulmonary fibrosis and cardiogenic pulmonary edema. The BALF active TGF-beta 1 levels were measured in 29 ARDS patients, with nine negative and six positive controls being enrolled also. The BALF from ARDS patients induced 41%...


Continuous Positive Airway Pressure Mean Arterial Pressure Acute Lung Injury Chronic Obstructive Pulmonary Disease Patient Acute Respiratory Distress Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Peter Andrews
    • 1
  • Elie Azoulay
    • 2
  • Massimo Antonelli
    • 3
  • Laurent Brochard
    • 4
    Email author
  • Christian Brun-Buisson
    • 5
  • Daniel de Backer
    • 6
  • Geoffrey Dobb
    • 7
  • Jean-Yves Fagon
    • 8
  • Herwig Gerlach
    • 9
  • Johan Groeneveld
    • 10
  • Jordi Mancebo
    • 11
  • Philipp Metnitz
    • 12
  • Stefano Nava
    • 13
  • Jerome Pugin
    • 14
  • Michael Pinsky
    • 15
  • Peter Radermacher
    • 16
  • Christian Richard
    • 17
  • Robert Tasker
    • 18
  1. 1.Intensive Care Medicine UnitWestern General HospitalEdinburghUK
  2. 2.Intensive Care Medicine UnitSaint Louis HospitalParisFrance
  3. 3.Department of Intensive Care and AnesthesiologyUniversita Cattolica del Sacro CuoreRomeItaly
  4. 4.Réanimation MédicaleAP-HP, Hôpital Henri MondorParis 12France
  5. 5.Medical Intensive Care UnitUniversity Hospital Henri MondorCreteilFrance
  6. 6.Service des Soins IntensifsHôpital ErasmeBruxellesBelgium
  7. 7.Intensive Care Medicine UnitRoyal Perth HospitalPerthAustralia
  8. 8.Intensive Care Medicine UnitEuropean Georges Pompidou HospitalParisFrance
  9. 9.Department of AnesthesiologyVivantes-Klinikum NeukoellnBerlinGermany
  10. 10.Intensive Care Medicine UnitVUMCAmsterdamThe Netherlands
  11. 11.Intensive Care Medicine UnitHospital Sant PauBarcelonaSpain
  12. 12.Department of Anesthesia and General Intensive Care MedicineUniversity Hospital of ViennaViennaAustria
  13. 13.Intensive Care Medicine UnitFondazione S. MaugeriPaviaItaly
  14. 14.Intensive Care Medicine UnitUniversity Hospital of GenevaGenevaSwitzerland
  15. 15.Intensive Care Medicine UnitUniversity of Pittsburgh Medical CenterPittsburghUSA
  16. 16.Department of AnesthesiaUniversity Medical School of UlmUlmGermany
  17. 17.Intensive Care Medicine UnitUniversity Hospital of Le Kremlin-BicetreLe Kremlin BicetreFrance
  18. 18.Pediatric Intensive Care UnitAddenbrooke's HospitalCambridgeUK

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