Intensive Care Medicine

, Volume 31, Issue 2, pp 177–188 | Cite as

Year in review in intensive care medicine, 2004. II. Brain injury, hemodynamic monitoring and treatment, pulmonary embolism, gastrointestinal tract, and renal failure

  • Peter Andrews
  • Elie Azoulay
  • Massimo Antonelli
  • Laurent BrochardEmail author
  • Christian Brun-Buisson
  • Geoffrey Dobb
  • Jean-Yves Fagon
  • Herwig Gerlach
  • Johan Groeneveld
  • Jordi Mancebo
  • Philipp Metnitz
  • Stefano Nava
  • Jerome Pugin
  • Michael Pinsky
  • Peter Radermacher
  • Christian Richard
  • Robert Tasker
  • Benoit Vallet
Year in Review 2004

Brain injury

The mismatching of demand and supply for organ donation has been highlighted in Intensive Care Medicine this year. A group from Paris [1] reported on their survey of patients admitted in severe coma in which they examined the implications for brain death identification and organ donation. This well conducted survey concludes that increasing the number of hospital donor/transplant coordinators in collaboration with mobile emergency units had led to identification of more comatose patients in ICU and more brain-dead patients. This endeavor had a direct effect on increasing the organ donation rate. This interesting report was accompanied by an editorial by Park [2]. The mismatch between demand and supply of organs was commented upon again and alternatives considered. These of course include living relative donation and the attendant risk of surgery, anesthesia, and postoperative care of the previously well donor. Opting-in, opting-out, presumed consent, and the logistics of...


Central Venous Pressure Brain Natriuretic Peptide Brain Death Fenoterol Terlipressin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Senouci K, Guerrini P, Diene E, Atinault A, Claquin J, Bonnet F, Tuppin P (2004) A survey on patients admitted in severe coma: implications for brain death identification and organ donation. Intensive Care Med 30:38–44CrossRefGoogle Scholar
  2. 2.
    Park G (2004) Supply and demand of organs for donation. Intensive Care Med 30:7–9CrossRefGoogle Scholar
  3. 3.
    Russell T (2004) Brain death. Intensive Care Med 30:1697–1698CrossRefGoogle Scholar
  4. 4.
    Leira EC, Bertrand ME, Hogan RE, Cruz-Flores S, Wyrwich KW, Albaker OJ, Holzemer EM (2004) Continuous or emergent EEG: can bedside caregivers recognize epileptiform discharges? Intensive Care Med 30:207–212CrossRefGoogle Scholar
  5. 5.
    Schneider G, Heglmeier S, Schneider J, Tempel G, Kochs EF (2004) Patient State Index (PSI) measures depth of sedation in intensive care patients. Intensive Care Med 30:213–216CrossRefGoogle Scholar
  6. 6.
    Walsh TS, Ramsay P, Kinnunen R (2004) Monitoring sedation in the intensive care unit: can “black boxes” help us? Intensive Care Med 30:1511–1513CrossRefGoogle Scholar
  7. 7.
    Ely EW, Truman B, Manzi DJ, Sigl JC, Shintani A, Bernard GR (2004) Consciousness monitoring in ventilated patients: bispectral EEG monitors arousal not delirium. Intensive Care Med 30:1537–1543CrossRefGoogle Scholar
  8. 8.
    Shehabi Y, Ruettimann U, Adamson H, Innes R, Ickeringill M (2004) Dexmedetomidine infusion for more than 24 hours in critically ill patients: sedative and cardiovascular effects. Intensive Care Med 30:2188–2196Google Scholar
  9. 9.
    Geffroy A, Bronchard R, Merckx P, Seince P-F, Faillot T, Albaladejo P, Marty J (2004) Severe traumatic head injury in adults: which patients are at risk of early hyperthermia? Intensive Care Med 30:785–790CrossRefGoogle Scholar
  10. 10.
    Dimopoulou I, Tsagarakis S, Theodorakopoulou M, Douka E, Zervou M, Kouyialis AT, Thalassinos N, Roussos C (2004) Endocrine abnormalities in critical care patients with moderate-to-severe head trauma: incidence, pattern and predisposing factors. Intensive Care Med 30:1051–1057CrossRefGoogle Scholar
  11. 11.
    Andrews PJ, Citerio G (2004) Intracranial pressure. I. historical overview and basic concepts. Intensive Care Med 30:1730–1733CrossRefGoogle Scholar
  12. 12.
    Savaridas T, Andrews PJ, Harris B (2004) Cortisol dynamics following acute severe brain injury. Intensive Care Med 30:1479–1483CrossRefGoogle Scholar
  13. 13.
    Johnston AJ, Steiner LA, Chatfield DA, Coles JP, Hutchinson PJ, Al-Rawi PG, Menon DK, Gupta AK (2004) Effect of cerebral perfusion pressure augmentation with dopamine and norepinephrine on global and focal brain oxygenation after traumatic brain injury. Intensive Care Med 30:791–797CrossRefGoogle Scholar
  14. 14.
    Johnston AJ, Steiner LA, O’Connell M, Chatfield DA, Gupta AK, Menon DK (2004) Pharmacokinetics and pharmacodynamics of dopamine and norepinephrine in critically ill head-injured patients. Intensive Care Med 30:45–50CrossRefGoogle Scholar
  15. 15.
    Steiner LA, Balestreri M, Johnston AJ, Czosnyka M, Coles JP, Chatfield DA, Smielewski P, Pickard JD, Menon DK (2004) Sustained moderate reductions in arterial CO (2) after brain trauma time-course of cerebral blood flow velocity and intracranial pressure. Intensive Care Med (e-pub ahead of print October 12)Google Scholar
  16. 16.
    Enblad P, Nilsson P, Chambers I, Citerio G, Fiddes H, Howells T, Kiening K, Ragauskas A, Sahuquillo J, Yau YH, Contant C, Piper I (2004) R3-survey of traumatic brain injury management in European brain IT centres year 2001. Intensive Care Med 30:1058–1065CrossRefGoogle Scholar
  17. 17.
    Martinez-Perez M, Bernabe F, Pena R, Fernandez R, Nahum A, Blanch L (2004) Effects of expiratory tracheal gas insufflation in patients with severe head trauma and acute lung injury. Intensive Care Med 30:2021–2027CrossRefGoogle Scholar
  18. 18.
    Rothoerl RD, Woertgen C, Brawanski A (2004) Hyperemia following aneurysmal subarachnoid hemorrhage: incidence, diagnosis, clinical features, and outcome. Intensive Care Med 30:1298–1302CrossRefGoogle Scholar
  19. 19.
    Macmillan C, Grant I, Andrews PJ (2002) Pulmonary and cardiac sequelae of subarachnoid haemorrhage: time for active management? Intensive Care Med 28:1012–1023CrossRefGoogle Scholar
  20. 20.
    Combes A, Berneau JB, Luyt CE, Trouillet JL (2004) Estimation of left ventricular systolic function by single transpulmonary thermodilution. Intensive Care Med 30:1377–1383CrossRefPubMedGoogle Scholar
  21. 21.
    Reinhart K, Kuhn HJ, Hartog C, Bredle DL (2004) Continuous central venous and pulmonary artery oxygen saturation monitoring in the critically ill. Intensive Care Med 30:1572–1578CrossRefPubMedGoogle Scholar
  22. 22.
    Desjardins R, Denault AY, Belisle S, Carrier M, Babin D, Levesque S, Martineau R (2004) Can peripheral venous pressure be interchangeable with central venous pressure in patients undergoing cardiac surgery? Intensive Care Med 30:627–632CrossRefGoogle Scholar
  23. 23.
    Staal EM, Baan J, Jukema JW, van der Wall EE, Steendijk P (2004) Transcardiac conductance for continuous measurement of left ventricular volume: validation vs. angiography in patients. Intensive Care Med 30:1370–1376CrossRefGoogle Scholar
  24. 24.
    Bremer F, Schiele A, Sagkob J, Palmaers T, Tschaikowsky K (2004) Perioperative monitoring of circulating and central blood volume in cardiac surgery by pulse dye densitometry. Intensive Care Med 30:2053–2059CrossRefGoogle Scholar
  25. 25.
    Gabbanelli V, Pantanetti S, Donati A, Montozzi A, Carbini C, Pelaia P (2004) Initial distribution volume of glucose as noninvasive indicator of cardiac preload: comparison with intrathoracic blood volume. Intensive Care Med 30:2067–2073CrossRefGoogle Scholar
  26. 26.
    Rocco M, Spadetta G, Morelli A, Dell’Utri D, Porzi P, Conti G, Pietropaoli P (2004) A comparative evaluation of thermodilution and partial CO2 rebreathing techniques for cardiac output assessment in critically ill patients during assisted ventilation. Intensive Care Med 30:82–87CrossRefGoogle Scholar
  27. 27.
    Vieillard-Baron A, Chergui K, Rabiller A, Peyrouset O, Page B, Beauchet A, Jardin F (2004) Superior vena caval collapsibility as a gauge of volume status in ventilated septic patients. Intensive Care Med 30:1734–1739PubMedGoogle Scholar
  28. 28.
    Barbier C, Loubieres Y, Schmit C, Hayon J, Ricome J-L, Jardin F, Vieillard-Baron A (2004) Respiratory changes in inferior vena cava diameter are helpful in predicting fluid responsiveness in ventilated septic patients. Intensive Care Med 30:1740–1746Google Scholar
  29. 29.
    Vignon P (2004) Evaluation of fluid responsiveness in ventilated septic patients: back to venous return. Intensive Care Med 30:1699–1701Google Scholar
  30. 30.
    Pinsky MR (2004) Using ventilation-induced aortic pressure and flow variation to diagnose preload responsiveness. Intensive Care Med 30:1008–1010CrossRefGoogle Scholar
  31. 31.
    Combes A, Arnoult F, Trouillet JL (2004) Tissue Doppler imaging estimation of pulmonary artery occlusion pressure in ICU patients. Intensive Care Med 30:75–81CrossRefGoogle Scholar
  32. 32.
    Dark PM, Singer M (2004) The validity of trans-esophageal Doppler ultrasonography as a measure of cardiac output in critically ill adults. Intensive Care Med 30:2060–2066CrossRefGoogle Scholar
  33. 33.
    Bahlmann L, Misfeld M, Klaus S, Leptien A, Heringlake M, Schmucker P, Sievers HH, Ungerstedt U, Kraatz EG (2004) Myocardial redox state during coronary artery bypass grafting assessed with microdialysis. Intensive Care Med 30:889–894CrossRefGoogle Scholar
  34. 34.
    Bendjelid K, Treggiari MM, Romand JA (2004) Transpulmonary lactate gradient after hypothermic cardiopulmonary bypass. Intensive Care Med 30:817–821CrossRefGoogle Scholar
  35. 35.
    Podbregar M, Voga G, Krivec B (2004) Morphologic characteristics of central pulmonary thromboemboli predict haemodynamic response in massive pulmonary embolism. Intensive Care Med 30:1552–1556CrossRefGoogle Scholar
  36. 36.
    Verschuren F, Heinonen E, Clause D, Roeseler J, Thys F, Meert P, Marion E, El Gariani A, Col J, Reynaert M, Liistro G (2004) Volumetric capnography as a bedside monitoring of thrombolysis in major pulmonary embolism. Intensive Care Med 30:2129–2132CrossRefGoogle Scholar
  37. 37.
    Kerbaul F, Collart F, Giorgi R, Oddoze C, Lejeune PJ, Guidon C, Caus T, Bellezza M, Gouin F (2004) Increased plasma levels of pro-brain natriuretic peptide in patients with cardiovascular complications following off-pump coronary artery surgery. Intensive Care Med 30:1799–1806CrossRefGoogle Scholar
  38. 38.
    Ray P, Arthaud M, Lefort Y, Birolleau S, Beigelman C, Riou B (2004) Usefulness of B-type natriuretic peptide in elderly patients with acute dyspnea. Intensive Care Med 30:2230–2236CrossRefGoogle Scholar
  39. 39.
    Geisser W, Vogt J, Wachter U, Hofbauer H, Georgieff M, Ensinger H (2004) Effects of dopexamine in comparison with fenoterol on carbohydrate, fat and protein metabolism in healthy volunteers. Intensive Care Med 30:702–708CrossRefGoogle Scholar
  40. 40.
    Schilling T, Grundling M, Strang CM, Moritz KU, Siegmund W, Hachenberg T (2004) Effects of dopexamine, dobutamine or dopamine on prolactin and thyreotropin serum concentrations in high-risk surgical patients. Intensive Care Med 30:1127–1133CrossRefGoogle Scholar
  41. 41.
    Morelli A, Rocco M, Conti G, Orecchioni A, De Gaetano A, Cortese G, Coluzzi F, Vernaglione E, Pelaia P, Pietropaoli P (2004) Effects of terlipressin on systematic and regional haemodynamics in catecholamine-treated hyperkinetic septic shock. Intensive Care Med 30:597–604CrossRefGoogle Scholar
  42. 42.
    Schortgen F, Deye N, Brochard L (2004) Preferred plasma volume expanders for critically ill patients: results of an international survey. Intensive Care Med 30:2222–2229Google Scholar
  43. 43.
    Boldt J, Ducke M, Kumle B, Papsdorf M, Zurmeyer EL (2004) Influence of different volume replacement strategies on inflammation and endothelial activation in the elderly undergoing major abdominal surgery. Intensive Care Med 30:416–422CrossRefPubMedGoogle Scholar
  44. 44.
    Kumar A, Anel R, Bunnell E, Habet K, Neumann A, Wolff D, Rosenson R, Cheang M, Parrillo JE (2004) Effect of large volume infusion on left ventricular volumes, performance and contractility parameters in normal volunteers. Intensive Care Med 30:1361–1369CrossRefGoogle Scholar
  45. 45.
    Nitenberg A (2004) Evaluation of left ventricular performance: an insolvable problem in human beings? The Graal quest. Intensive Care Med 30:1258–1260CrossRefGoogle Scholar
  46. 46.
    Molnar Z, Mikor A, Leiner T, Szakmany T (2004) Fluid resuscitation with colloids of different molecular weight in septic shock. Intensive Care Med 30:1356–1360Google Scholar
  47. 47.
    Schmidt H, Muller-Werdan U, Nuding S, Hoffmann T, Francis DP, Hoyer D, Rauchhaus M, Werdan K (2004) Impaired chemoreflex sensitivity in adult patients with multiple organ dysfunction syndrome—the potential role of disease severity. Intensive Care Med 30:665–672CrossRefPubMedGoogle Scholar
  48. 48.
    Bahloul M, Ben Hamida C, Chtourou K, Ksibi H, Dammak H, Kallel H, Chaari A, Chelly H, Guermazi F, Rekik N, Bouaziz M (2004) Evidence of myocardial ischaemia in severe scorpion envenomation. Myocardial perfusion scintigraphy study. Intensive Care Med 30:461–467CrossRefGoogle Scholar
  49. 49.
    Slagt C, Innes R, Bihari D, Lawrence J, Shehabi Y (2004) A novel method for insertion of post-pyloric feeding tubes at the bedside without endoscopic or fluoroscopic assistance: a prospective study. Intensive Care Med 30:103–107CrossRefGoogle Scholar
  50. 50.
    Tjader I, Rooyackers O, Forsberg AM, Vesali RF, Garlick PJ, Wernerman J (2004) Effects on skeletal muscle of intravenous glutamine supplementation to ICU patients. Intensive Care Med 30:266–275CrossRefPubMedGoogle Scholar
  51. 51.
    Rabe C, Schmitz V, Paashaus M, Musch A, Zickermann H, Dumoulin FL, Sauerbruch T, Caselmann WH (2004) Does intubation really equal death in cirrhotic patients? Factors influencing outcome in patients with liver cirrhosis requiring mechanical ventilation. Intensive Care Med 30:1564–1571CrossRefGoogle Scholar
  52. 52.
    Berghe G van den, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouillon R (2001) Intensive insulin therapy in the critically ill patients. N Engl J Med 345:1359–1367CrossRefPubMedGoogle Scholar
  53. 53.
    McMullin J, Brozek J, Jaeschke R, Hamielec C, Dhingra V, Rocker G, Freitag A, Gibson J, Cook D (2004) Glycemic control in the ICU: a multicenter survey. Intensive Care Med 30:798–803CrossRefPubMedGoogle Scholar
  54. 54.
    Iapichino G, Gattinoni L, Radrizzani D, Simini B, Bertolini G, Ferla L, Mistraletti G, Porta F, Miranda DR (2004) Volume of activity and occupancy rate in intensive care units. Association with mortality. Intensive Care Med 30:290–297CrossRefGoogle Scholar
  55. 55.
    Opdam HI, Silvester W (2004) Identifying the potential organ donor: an audit of hospital deaths. Intensive Care Med 30:1390–1397CrossRefGoogle Scholar
  56. 56.
    Sward K, Valsson F, Sellgren J, Ricksten SE (2004) Bedside estimation of absolute renal blood flow and glomerular filtration rate in the intensive care unit. A validation of two independent methods. Intensive Care Med 30:1776–1782Google Scholar
  57. 57.
    Bollmann MD, Revelly JP, Tappy L, Berger MM, Schaller MD, Cayeux MC, Martinez A, Chiolero RL (2004) Effect of bicarbonate and lactate buffer on glucose and lactate metabolism during hemodiafiltration in patients with multiple organ failure. Intensive Care Med 30:1103–1110CrossRefGoogle Scholar
  58. 58.
    Monchi M, Berghmans D, Ledoux D, Canivet JL, Dubois B, Damas P (2004) Citrate vs. heparin for anticoagulation in continuous venovenous hemofiltration: a prospective randomized study. Intensive Care Med 30:260–265CrossRefGoogle Scholar
  59. 59.
    Baldwin I, Bellomo R, Koch B (2004) Blood flow reductions during continuous renal replacement therapy and circuit life. Intensive Care Med 30:2074–2079CrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Peter Andrews
    • 1
  • Elie Azoulay
    • 2
  • Massimo Antonelli
    • 3
  • Laurent Brochard
    • 4
    Email author
  • Christian Brun-Buisson
    • 5
  • Geoffrey Dobb
    • 6
  • Jean-Yves Fagon
    • 7
  • Herwig Gerlach
    • 8
  • Johan Groeneveld
    • 9
  • Jordi Mancebo
    • 10
  • Philipp Metnitz
    • 11
  • Stefano Nava
    • 12
  • Jerome Pugin
    • 13
  • Michael Pinsky
    • 14
  • Peter Radermacher
    • 15
  • Christian Richard
    • 16
  • Robert Tasker
    • 17
  • Benoit Vallet
    • 18
  1. 1.Intensive Care Medicine UnitWestern General HospitalEdinburghUK
  2. 2.Intensive Care Medicine UnitSaint Louis HospitalParisFrance
  3. 3.Department of Intensive Care and AnesthesiologyUniversità Cattolica del Sacro CuoreRomeItaly
  4. 4.Medical Intensive Care UnitUniversity Hospital Henri MondorCreteilFrance
  5. 5.Medical Intensive Care UnitUniversity Hospital Henri MondorCreteilFrance
  6. 6.Intensive Care Medicine UnitRoyal Perth HospitalPerthAustralia
  7. 7.Intensive Care Medicine UnitEuropean Georges Pompidou HospitalParisFrance
  8. 8.Department of AnesthesiologyVivantes-Klinikum NeukoellnBerlinGermany
  9. 9.Intensive Care Medicine UnitVUMCAmsterdamThe Netherlands
  10. 10.Intensive Care Medicine UnitHospital Sant PauBarcelonaSpain
  11. 11.Department of Anesthesia and General Intensive Care MedicineUniversity Hospital of ViennaViennaAustria
  12. 12.Intensive Care Medicine UnitFondazione S. MaugeriPaviaItaly
  13. 13.Intensive Care Medicine UnitUniversity Hospital of GenevaGenevaSwitzerland
  14. 14.Intensive Care Medicine UnitUniversity of Pittsburgh Medical CenterPittsburghUSA
  15. 15.Department of AnesthesiaUniversity Medical School of UlmUlmGermany
  16. 16.Intensive Care Medicine UnitUniversity Hospital of Le Kremlin-BicetreLe Kremlin BicetreFrance
  17. 17.Pediatric Intensive Care UnitAddenbrooke’s HospitalCambridgeUK
  18. 18.Department of Anesthesiology and Intensive CareUniversity Hospital of LilleLilleFrance

Personalised recommendations