Intensive Care Medicine

, Volume 30, Issue 12, pp 2245–2252 | Cite as

Performance of two measures of general health-related quality of life, the EQ-5D and the RAND-36 among critically ill patients

  • Anne Kaarlola
  • Ville Pettilä
  • Pertti Kekki



To compare two health-related quality of life measures, the preference-based EQ-5D with five questions and the profile-based RAND-36 with 36 questions, in previous critically ill patients.


Prospective observational study.


A ten-bed medical-surgical intensive care unit (ICU) in a tertiary care university hospital.


Of the 2,709 critically ill patients, treated during the years 1995–2000, the 1,099 patients of the 1,443 still alive who returned both mailed measures were included in the study.



Measurements and main results

The EQ-5D and the RAND-36 correlated well (P <.001). Ceiling effect was more obvious with the EQ-5D; the values of the RAND-36 varied usually from 0 to 100 in all the three levels of the corresponding EQ-5D question, and the weakest statistically significant differences were between the EQ levels 2 and 3. In particular, the RAND-36 proved to differentiate better the levels of mobility, self-care, and poor outcome.


The EQ-5D and the RAND-36 correlated well, but when more precisely stated information is needed, especially regarding mobility, self-care, or low quality of life levels of previous critically ill patients, the profile-based RAND-36 may discriminate better.


Outcome Quality of life EQ-5D RAND-36 ICU Adults 



We are very thankful to S. Sarna for statistical advice

Supplementary material

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(PDF 59 KB)


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Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  1. 1.Department of Anaesthesiology and Intensive Care Medicine, Meilahti HospitalHelsinki University Central HospitalFinland
  2. 2.Department of General Practice and Primary Health CareUniversity of HelsinkiHelsinkiFinland

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