Performance of two measures of general health-related quality of life, the EQ-5D and the RAND-36 among critically ill patients
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To compare two health-related quality of life measures, the preference-based EQ-5D with five questions and the profile-based RAND-36 with 36 questions, in previous critically ill patients.
Prospective observational study.
A ten-bed medical-surgical intensive care unit (ICU) in a tertiary care university hospital.
Of the 2,709 critically ill patients, treated during the years 1995–2000, the 1,099 patients of the 1,443 still alive who returned both mailed measures were included in the study.
Measurements and main results
The EQ-5D and the RAND-36 correlated well (P <.001). Ceiling effect was more obvious with the EQ-5D; the values of the RAND-36 varied usually from 0 to 100 in all the three levels of the corresponding EQ-5D question, and the weakest statistically significant differences were between the EQ levels 2 and 3. In particular, the RAND-36 proved to differentiate better the levels of mobility, self-care, and poor outcome.
The EQ-5D and the RAND-36 correlated well, but when more precisely stated information is needed, especially regarding mobility, self-care, or low quality of life levels of previous critically ill patients, the profile-based RAND-36 may discriminate better.
KeywordsOutcome Quality of life EQ-5D RAND-36 ICU Adults
We are very thankful to S. Sarna for statistical advice
- 3.Bowling A (1997) Evaluating health services: multidisciplinary collaboration. In: Research methods in health care. Open University, Buckingham Philadelphia, pp 6–15Google Scholar
- 5.Jones I (1997) Costing health services: health economics. In: Bowling A (ed) Research methods in health care. Open University, Buckingham Philadelphia, pp 79–97Google Scholar
- 6.Kutsogiannis DJ, Noseworthy T (2001) Health-related quality of life; during and following critical care. In: Sibbald JW, Bion JF (eds) Evaluating critical care. Springer, Berlin Heidelberg New York, pp 86–103Google Scholar
- 7.Kerridge RK, Glasziou PP, Hillman KM (1995) The use of “quality-adjusted life years” (QALYs) to evaluate treatment in intensive care. Anaesth Intens Care 23:322–331Google Scholar
- 11.Hunt SM, McKenna SP, McEwen J, Williams J, Papp E (1981) The Nottingham health profile: subjective health status and medical consultations. Soc Sci Med 15:221–229Google Scholar
- 12.Ware MK, Snow KK, Kosinski M, Gandek B (1993) SF-36 Health survey: manual and interpretation guide. The Health Institute, New England Medical Centre, BostonGoogle Scholar
- 13.Kind P, Rosser RM, Williams A (1982) Valuation of quality of life; some psychometric evidence. In: Jones-Lee MW (ed) The value of life and safety. Elsevier, AmsterdamGoogle Scholar
- 17.Bowling A (1997) The principles of research. In: Research methods in health care. Open University, Buckingham Philadelphia, pp 130–138Google Scholar
- 19.Ohinmaa A, Sintonen H (1996) Quality of life of Finnish population measures by EuroQol. In: Badia X, Herdman M, Segura A (eds) EuroQol, Plenary Meeting. Barcelona 1995, 3–5 October. Discussion papers, Catalan Institute of Public Health, Barcelona, pp 161–172Google Scholar
- 20.Aalto A, Aro S, Aro AR, Mähönen M (1999) RAND 36-item Survey 1.0. Finnish version. STAKES (National Research and Development Centre for Welfare and Health), HelsinkiGoogle Scholar
- 22.Ware JE, Kosinski M, Keller SD (1994) SF-36 Physical and mental health summary scales. A user’s manual. Health Assessment Lab, Boston MAGoogle Scholar
- 35.Schelling G, Richter M, Roozendaal B, Rothenhäusler HB, Krauseneck T, Stoll C, Nollert G, Schmidt M, Kapfhammer HP (2003) Exposure to high stress in the intensive care unit may have negative effects on health-related quality-of-life outcome after cardiac surgery. Crit Care Med 31:1971–1980CrossRefPubMedGoogle Scholar
- 38.Schelling G, Stoll C, Haller M, Briegel J, Manert W, Hummel T, Lenhart A, Heyduck M, Polasek J, Meier M, Preuss U, Bullinger M, Schuffel W, Peter K (1998) Health-related quality of life and posttraumatic stress disorder in survivors of the acute respiratory distress syndrome. Crit Care Med 26:651–659CrossRefPubMedGoogle Scholar
- 39.Skogstad W (2000) Working in the world of bodies. A medical ward. In: Hinshelwood RD, Skogstad W (eds) Observing organisations. Anxiety, defence and culture in health care. Routledge, London, pp 101–121Google Scholar
- 40.Bion WR (1961) Experiences in groups. Routledge, Bristol, pp 59–75Google Scholar