Intensive Care Medicine

, Volume 30, Issue 7, pp 1266–1275 | Cite as

Year in review in intensive care medicine: 2003. II. Brain injury, hemodynamics, gastrointestinal tract, renal failure, metabolism, trauma, and postoperative

  • Edward Abraham
  • Peter Andrews
  • Massimo Antonelli
  • Laurent BrochardEmail author
  • Christian Brun-Buisson
  • Geoffrey Dobb
  • Jean-Yves Fagon
  • Johan Groeneveld
  • Jordi Mancebo
  • Philipp Metnitz
  • Stefano Nava
  • Michael Pinsky
  • Peter Radermacher
  • Marco Ranieri
  • Christian Richard
  • Robert Tasker
  • Benoit Vallet
Special Article

Brain injury

Considerable interest remains in measuring cerebral blood flow and in ascertaining the adequacy of cerebral blood flow, cerebral perfusion pressure, and substrate delivery/metabolism after acute brain injury. Researchers today are dogged by the same problem that faced pioneers many decades ago: that the brain is inaccessible within the skull. The combined technologies of magnetic resonance imaging, positron emission tomography, transcranial Doppler ultrasound, near infrared reflectance spectroscopy (NIRS), and cerebral microdialysis offer the prospect of better understanding the basic regulatory mechanisms that remain to be elucidated in neurophysiology. Cross-sectional imaging/signals offer the potential for spatial resolution but cannot provide the vigilance desirable in critical care monitoring, and bedside monitors measure either indirect variables or regional variables that may not accurately reflect other brain subregions. What is required is a “bottom-up” modeling...


Cerebral Blood Flow Acute Renal Failure Cerebral Perfusion Pressure Flunitrazepam Dengue Hemorrhagic Fever 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Edward Abraham
    • 1
  • Peter Andrews
    • 2
  • Massimo Antonelli
    • 3
  • Laurent Brochard
    • 4
    Email author
  • Christian Brun-Buisson
    • 4
  • Geoffrey Dobb
    • 5
  • Jean-Yves Fagon
    • 6
  • Johan Groeneveld
    • 7
  • Jordi Mancebo
    • 8
  • Philipp Metnitz
    • 9
  • Stefano Nava
    • 10
  • Michael Pinsky
    • 11
  • Peter Radermacher
    • 12
  • Marco Ranieri
    • 13
  • Christian Richard
    • 14
  • Robert Tasker
    • 15
  • Benoit Vallet
    • 16
  1. 1.Division of Pulmonary and Critical Care Medicine, Department of Medicine, Health Sciences CenterUniversity of ColoradoDenverUSA
  2. 2.Intensive Care UnitWestern General HospitalEdinburghUK
  3. 3.Department of Intensive Care and AnesthesiologyPoliclinico UniversitarioRomeItaly
  4. 4.Medical Intensive Care UnitUniversity Hospital Henri MondorCreteilFrance
  5. 5.Intensive Care UnitRoyal Perth HospitalPerthAustralia
  6. 6.Medical Intensive Care UnitUniversity European Hospital Georges PompidouParisFrance
  7. 7.Medical Intensive Care UnitFree University HospitalAmsterdamThe Netherlands
  8. 8.Servei Medicina IntensivaHospital Sant Pau.BarcelonaSpain
  9. 9.Department of Anesthesia and General Intensive Care MedicineUniversity Hospital of ViennaViennaAustria
  10. 10.Respiratory Intensive Care UnitFondazione S. MaugeriPaviaItaly
  11. 11.Intensive Care Medicine, Medical CenterUniversity of PittsburghPittsburghUSA
  12. 12.Department of AnesthesiaUniversity Medical School of UlmUlmGermany
  13. 13.Anestesiologia e Rianimazione, Ospedale S Giovanni BattistaUniversita di TorinoTurinItaly
  14. 14.Intensive Care UnitUniversity Hospital of BicetreLe Kremlin BicetreFrance
  15. 15.Department of Paediatrics, Addenbrooke’s HospitalCambridge University School of MedicineCambridgeUK
  16. 16.Department of Anesthesiology and Intensive CareUniversity Hospital of LilleLilleFrance

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