Intensive Care Medicine

, Volume 30, Issue 5, pp 811–816 | Cite as

Body temperature alterations in the critically ill

  • Daliana Peres Bota
  • Flavio Lopes Ferreira
  • Christian Mélot
  • Jean Louis Vincent



To determine the incidence of body temperature (BT) alterations in critically ill patients, and their relationship with infection and outcome.


Prospective, observational study.


Thirty-one bed, medico-surgical department of intensive care.


Adult patients admitted consecutively to the ICU for at least 24 h, during 6 summer months.




Fever (BT≥38.3°C) occurred in 139 (28.2%) patients and hypothermia (BT≤36°C) in 45 (9.1%) patients, at some time during the ICU stay. Fever was present in 52 of 100 (52.0%) infected patients without septic shock, and in 24 of 38 (63.2%) patients with septic shock. Hypothermia occurred in 5 of 100 (5.0%) infected patients without septic shock and in 5 of 38 (13.1%) patients with septic shock. Patients with hypothermia and fever had higher Sequential Organ Failure Assessment (SOFA) scores on admission (6.3±3.7 and 6.4±3.3 vs 4.6±3.2; p<0.01), maximum SOFA scores during ICU stay (7.6±5.2 and 8.2±4.7 vs 5.4±3.8; p<0.01) and mortality rates (33.3 and 35.3% vs 10.3%; p<0.01). The length of stay (LOS) was longer in febrile patients than in hypothermic and normothermic (36°C<BT<38.3°C) patients [median 6 (1–57) vs 5 (2–28) and 3 (1–33) days, p=0.02 and p=0.01, respectively). Among the septic patients hypothermic patients were older than febrile patients (69±9 vs 54±7 years, p=0.01). Patients with septic shock had a higher mortality if they were hypothermic than if they were febrile (80 vs 50%, p<0.01).


Both hypothermia and fever are associated with increased morbidity and mortality rates. Patients with hypothermia have a worse prognosis than those with fever.


Hypothermia Normothermia Fever Infection Septic shock Organ failure Length of stay 


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Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Daliana Peres Bota
    • 1
  • Flavio Lopes Ferreira
    • 1
  • Christian Mélot
    • 1
  • Jean Louis Vincent
    • 1
  1. 1.Department of Intensive CareErasme University Hospital, Free University of BrusselsBrusselsBelgium

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