Intensive Care Medicine

, Volume 30, Issue 1, pp 33–37 | Cite as

Defining acute renal failure: physiological principles

Physiological Note


  1. 1.
    De Mendonca A, Vincent J-L, Suter PM et al. (2000) Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score. Intensive Care Med 26:915–921Google Scholar
  2. 2.
    Chertow GM, Levy EM, Hammermeister KE, Grover F, Daley J (1998) Independent association between acute renal failure and mortality following cardiac surgery. Am J Med 104:343–348CrossRefGoogle Scholar
  3. 3.
    Bosch JP, Lauer A, Glabman S (1984) Short-term protein loading in assessment of patients with renal disease. Am J Med 77:873–879PubMedGoogle Scholar
  4. 4.
    Bosch JP, Saccaggi A, Lauer A, Ronco C, Belledonne M, Glabman S (1983) Renal functional reserve in humans. Effect of protein intake on glomerular filtration rate. Am J Med 75:943–950PubMedGoogle Scholar
  5. 5.
    Bosch JP, Lew S, Glabman S, Lauer A (1986) Renal hemodynamic changes in humans. Response to protein loading in normal and diseased kidneys. Am J Med 81:809–815PubMedGoogle Scholar
  6. 6.
    Ronco C, Brendolan A, Bragantini L, Chiaramonte S, Fabris A, Feriani M, Dell Aquila R, Milan M, Mentasti P, La Greca G (1988) Renal functional reserve in pregnancy. Nephrol Dial Transplant 3:157–161PubMedGoogle Scholar
  7. 7.
    Levey AS (1990) Measurement of renal function in chronic renal disease. Kidney Int 38:167–173PubMedGoogle Scholar
  8. 8.
    Perrone RD, Madias NE, Levey AS (1992) Serum creatinine as an index of renal function: new insights into old concepts. Clin Chem 38:1933–1953PubMedGoogle Scholar
  9. 9.
    Clark WR, Ronco C (1998) Renal replacement therapy in acute renal failure: solute removal mechanisms and dose quantification. Kidney Int (Suppl) 53:S133–S137Google Scholar
  10. 10.
    Doolan PD, Alpen EL, Theil GB (1962) A clinical appraisal of the plasma concentration and endogenous clearance of creatinine. Am J Med 32:65–72PubMedGoogle Scholar
  11. 11.
    Kim KE, Onesti G, Ramirez O (1969) Creatinine clearance in renal disease. A reappraisal. BMJ 4:11–19PubMedGoogle Scholar
  12. 12.
    Branstrom E, Grzegorczyk A, Jacobsson L (1998) GFR measurement with iohexol and 51Cr-EDTA. A comparison of the two favoured GFR markers in Europe. Nephrol Dial Transplant 13:1176–1181CrossRefPubMedGoogle Scholar
  13. 13.
    Han WK, Bailly V, Abichandani R et al. (2002) Kidney injury molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int 62:237–244CrossRefGoogle Scholar
  14. 14.
    Jovanovic D, Krstivojevic P, Obradovic I, Durdevic V, Dukanovic L (2003) Serum cystatin C and beta2-microglobulin as markers of glomerular filtration rate. Ren Fail 25:123–133CrossRefPubMedGoogle Scholar
  15. 15.
    Herget-Rosenthal S, Marggraf G, Goering F, Phillip T, Kribben A (2003) Can serum cystatin C detect acute renal failure? (abstract). ISN-ERA/EDTA World Congress of Nephrology, Berlin:O11Google Scholar
  16. 16.
    Fliser D, Franek E, Joest M et al (1997) Renal function in the elderly: impact of hypertension and cardiac function. Kidney Int 51:1196–1204PubMedGoogle Scholar
  17. 17.
    National Kidney Foundation. K/DOQI (2002) Clinical practice guidelines for chronic kidney disease; evaluation, classification and stratification. Am J Kidney Dis (Suppl) 39:S76–S92Google Scholar
  18. 18.
    Bellomo R, Kellum J, Ronco C (2001) Acute renal failure: time for consensus. Intensive Care Med 27:1685–1688CrossRefPubMedGoogle Scholar
  19. 19.
    Kellum JA, Mehta RL, Ronco C (2001) Acute dialysis quality initiative (ADQI). Contrib Nephrol 132:258–265PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Rinaldo Bellomo
    • 1
  • John A. Kellum
    • 2
  • Claudio Ronco
    • 3
  1. 1.Department of Intensive Care and Division of SurgeryAustin & Repatriation Medical CentreHeidelberg, MelbourneAustralia
  2. 2.Division of Critical Care Medicine, Scaife HallUniversity of Pittsburgh Medial CentrePittsburghUSA
  3. 3.Divisione di NefrologiaOspedale San BortoloVicenzaItaly

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