Pulmonary vascular resistance
- 608 Downloads
Almost 20 years ago, Adriaan Versprille published an editorial in this journal to explain why, in his opinion, the calculation of pulmonary vascular resistance (PVR) is meaningless . The uncertainties of PVR were underscored a year later by McGregor and Sniderman in the American Journal of Cardiology . Obviously, both papers failed to convince. A Medline search from 1985 to the end of 2002 reveals no less than 7,158 papers with PVR calculations. What is it that could be wrong in all this literature?
What is a resistance calculation?
- 3.Landis EM (1982) The capillary circulation. In: Fishman AP, RichardsDW (eds) Circulation of the Blood. Men and Ideas. American Physiological Society, Bethesda, Maryland, pp 355–406Google Scholar
- 4.Permutt S, Bromberger-Barnea B, Bane HN (1962) Alveolar pressure, pulmonary venous pressure and the vascular waterfall. Med Thorac 19:239–260Google Scholar
- 6.Mélot C, Delcroix M, Lejeune P, Leeman M, Naeije R (1995) Starling resistor versus viscoelastic models for embolic pulmonary hypertension. Am J Physiol 267 (Heart Circ Physiol 36:H817–827)Google Scholar
- 10.Pagnamenta A, Fesler P, Vandivinit A, Brimioulle S, Naeije R (2003) Pulmonary vascular effects of dobutamine in experimental pulmonary hypertension. Crit Care Med (in press)Google Scholar