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Binary Dispersive Liquid-Liquid Microextraction Strategy for Accurate and Precise Determination of Micropollutants in Lake, Well and Wastewater Matrices

  • Hanife Sari ErkanEmail author
  • Dotse Selali Chormey
  • Abdulkadir Caglak
  • Gamze Dalgic Bozyigit
  • Esra Maltepe
  • Güleda Onkal Engin
  • Sezgin Bakırdere
Article

Abstract

In this study, a binary mixture in dispersive liquid-liquid microextraction was used for the preconcentration and determination of selected pesticides, pharmaceutical and hormone by GC–MS. A Box–Behnken experimental design was used to optimize the amounts of binary mixture, dispersive solvent and salt. The optimum parameters obtained were dichloromethane/1,2-dichloroethane binary mixture (200 µL), ethanol (2.0 mL) and potassium nitrate (1.0 g). Analytical performance of each analyte was determined under the optimum conditions and the lowest and highest detection limits calculated were 0.43 and 5.9 ng/mL. Low relative standard deviations were obtained even in the lowest concentrations in linear calibration plots, signifying high precision for the sample preparation procedure and instrumental measurement. Accuracy of the developed method and applicability to real samples was tested on well, lake, hospital and municipal wastewater. The percent recoveries acquired at different spiked concentrations were satisfactory (89%–108%), validating the accuracy of the method for the quantification of the analytes in the selected matrices.

Keywords

Pesticide B-DLLME GC–MS Wastewater Experimental design 

References

  1. Alkan E, Kapukıran F, Er EÖ, Chormey DS, Keyf S, Özdoğan N, Bakırdere S (2018) Simultaneous determination of phorate and oxyfluorfen in well water samples with high accuracy by GC-MS after binary dispersive liquid-liquid microextraction. Water Air Soil Pollut 229:298CrossRefGoogle Scholar
  2. Caliman FA, Gavrilescu M (2009) Pharmaceuticals, personal care products andendocrine disrupting agents in the environment—a review. Clean Soil Air Water 37:277–303CrossRefGoogle Scholar
  3. Chormey DS, Bodur S, Baskin D, Firat M, Bakirdere S (2018) Accurate and sensitive determination of selected hormones, endocrine disruptors, and pesticides by gas chromatography-mass spectrometry after the multivariate optimization of switchable solvent liquid-phase microextraction. J Sep Sci 41:2895–2902CrossRefGoogle Scholar
  4. Díaz-Cruz MS, López de Alda MJ, López R, Barceló D (2003) Determination of estrogens and progestogens by mass spectrometric techniques (GC/MS, LC/MS and LC/MS/MS). J Mass Spectrom 38:917–923CrossRefGoogle Scholar
  5. Eggen RI, Hollender J, Joss A, Scharer M, Stamm C (2014) Reducing the discharge of micropollutants in the aquatic environment: the benefits of upgrading wastewater treatment plants. Environ Sci Technol 48:7683–7689CrossRefGoogle Scholar
  6. Estevão PL, Peralta-Zamora P, Nagata N (2014) Binary solvent dispersive liquid-liquid microextraction for the determination of pesticides in natural water samples. J Braz Chem Soc 29:2104–2116Google Scholar
  7. Gao R, Wang J (2007) Effects of pH and temperature on isotherm parameters of chlorophenolsbiosorption to anaerobic granular sludge. J Hazard Mater 145:398–403CrossRefGoogle Scholar
  8. Gondo TT, Obuseng VC, Mmualefe LC, Okatch H (2016) Employing solid phase microextraction as extraction tool for pesticide residues in traditional medicinal plants. J Anal Methods Chem 2016:2890219CrossRefGoogle Scholar
  9. Grobler DF, Badenhorst JE, Kempster PL (1996) PCBs, chlorinated hydrocarbon pesticides and chlorophenols in the Isipingo Estuary, Natal, Republic of South Africa. Mar Pollut Bull 32:572–575CrossRefGoogle Scholar
  10. Hameed BH, El-Khaiary MI (2008) Malachite green adsorption by rattan sawdust: isotherm, kinetic and mechanism modeling. J Hazard Mater 159:574–579CrossRefGoogle Scholar
  11. Hodson PV, Thivierge D, Levesque MC, McWhirter M, Ralph K, Gray B, Carey JH, Van der Kraak G, Whittle DM (1992) Effects of bleached kraft mill effluent on fish in the St. Maurice River, Quebec. Environ Toxicol Chem 11:1635–1651CrossRefGoogle Scholar
  12. Hunter AL (2015) Assessment of estrogenic compounds in a wastewater treatment plant influent and effluent. Bachelor of Science with Honors College Graduate Distinction at Western Kentucky University. https://digitalcommons.wku.edu/cgi/viewcontent.cgi?referer=https://scholar.google.com.tr/&httpsredir=1&article=1591&context=stu_hon_theses. Accessed 17 Jan 2019
  13. Ibrahim MW, Mohamad AA, Ahmed AM (2018) Application of GC-MS in determination of malathion in environmental samples. World J Pharm Pharm Sci 7:135–143Google Scholar
  14. Kiarostami V, Rouini MR, Mohammadian R, Lavasani H, Ghazaghi M (2014) Binary solvents dispersive liquid-liquid microextraction (BS-DLLME) method for determination of tramadol in urine using high-performance liquid chromatography. J Pharm Sci 22:25Google Scholar
  15. Kostich MS, Batt AL, Lazorchak JM (2014) Concentrations of prioritized pharmaceuticals in effluents from 50 large wastewater treatment plants in the US and implications for risk estimation. Environ Pollut 184:354–359CrossRefGoogle Scholar
  16. Liu Q, Chen D, Wu J, Yin G, Lin Q, Zhang M, Hu H (2018) Determination of phthalate esters in soil using a quick, easy, cheap, effective, rugged, and safe method followed by GC–MS. J Sep Sci 41:1812–1820CrossRefGoogle Scholar
  17. Luo Y, Guo W, Ngo HH, Nghiem LD, Hai FI, Zhang J, Liang S, Wang XC (2014) A review on the occurrence of micropollutants in the aquatic environment and their fate and removal during wastewater treatment. Sci Total Environ 473–474:619–641CrossRefGoogle Scholar
  18. Ma XY, Li Q, Wang XC, Wang Y, Wang D, Ngo HH (2018) Micropollutants removal and health risk reduction in a water reclamation and ecological reuse system. Water Res 138:272–281CrossRefGoogle Scholar
  19. Maham M, Karami-Osboo R, Kiarostami V, Waqif-Husain S (2013) Novel binary solvents-dispersive liquid-liquid microextraction (BS-DLLME) method for determination of patulin in apple juice using high-performance liquid chromatography. Food Anal Methods 6:761–766CrossRefGoogle Scholar
  20. Matisova E, Hrouzkova S (2012) Analysis of endocrine disrupting pesticides by capillary GC with mass spectrometric detection. Int J Environ Res Public Health 9:3166–3196CrossRefGoogle Scholar
  21. Mekonen S, Argaw R, Simanesew A, Houbraken M, Senaeve D, Ambelu A, Spanoghe P (2016) Pesticide residues in drinking water and associated risk to consumers in Ethiopia. Chemosphere 162:252–260CrossRefGoogle Scholar
  22. Melvin SD (2017) Effect of antidepressants on circadian rhythms in fish: insights and implications regarding the design of behavioural toxicity tests. Aquat Toxicol 182:20–30CrossRefGoogle Scholar
  23. Muhamad A, Karim ATA, Zakaria NF, Rapok KJA (2016) Determination of phthalate ester compounds in Sembrong river sediment. J Techno Soc 8:1–8Google Scholar
  24. Pakade YB, Tewary DK (2010) Development and applications of single-drop microextraction for pesticide residue analysis: a review. J Sep Sci 33:3683–3691CrossRefGoogle Scholar
  25. Pal A, Gin KY, Lin AY, Reinhard M (2010) Impacts of emerging organic contaminants on freshwater resources: review of recent occurrences, sources, fate and effects. Sci Total Environ 408:6062–6069CrossRefGoogle Scholar
  26. Roger G, Francisco SB, Francisco C, Marco MP (2002) Indirect competitive immunoassay for trichlorophenol determination: rational evaluation of the competitor heterology effect. Anal Chim Acta 452:191–206CrossRefGoogle Scholar
  27. Roy JR, Chakraborty S, Chakraborty TR (2009) Estrogen-like endocrine disrupting chemicals affecting puberty in humans—a review. Med Sci Monit 15:137–145Google Scholar
  28. Salaudeen T, Okoh O, Agunbiade F, Okoh A (2018) Fate and impact of phthalates in activated sludge treated municipal wastewater on the water bodies in the Eastern Cape, South Africa. Chemosphere 203:336–344CrossRefGoogle Scholar
  29. Sarkar S, Ali S, Rehmann L, Nakhla G, Ray MB (2014) Degradation of estrone in water and wastewater by various advanced oxidation processes. J Hazard Mater 278:16–24CrossRefGoogle Scholar
  30. Shao HY, Wu MH, Deng F, Xu G, Liu N, Li X, Tang L (2018) Electron beam irradiation induced degradation of antidepressant drug fluoxetine in water matrices. Chemosphere 190:184–190CrossRefGoogle Scholar
  31. Viñas P, Campillo N, Andruch V (2015) Recent achievements in solidified floating organic drop microextraction. Trends Anal Chem 68:48–77CrossRefGoogle Scholar
  32. Wang X, Wang Y, Zou X, Cao Y (2014) Improved dispersive liquid-liquid microextraction based on the solidification of floating organic droplet method with a binary mixed solvent applied for determination of nicotine and cotinine in urine. Anal Methods 6:2384–2389CrossRefGoogle Scholar
  33. Wang Y, Miao X, Wei H, Liu D, Xia G, Yang X (2016) Dispersive liquid-liquid microextraction combined with gas chromatography-mass spectrometry for the determination of multiple pesticides in celery. Food Anal Methods 9:2133–2141CrossRefGoogle Scholar
  34. Wu J, Ma T, Zhou Z, Yu N, He Z, Li B, Shi Y, Ma D (2018) Occurrence and fate of phthalate esters in wastewater treatment plants in Qingdao. Hum Ecol Risk Assess.  https://doi.org/10.1080/10807039.2018.1471341 CrossRefGoogle Scholar
  35. Xiao-Huan Z, Qiu-Hua W, Zhang M-Y, Guo-Hong X, Zhi W (2009) Developments of dispersive liquid-liquid microextraction technique. Chin J Anal Chem 37:161–168CrossRefGoogle Scholar
  36. Yilmaz B, Kadioglu Y (2017) Determination of 17 β-estradiol in pharmaceutical preparation by UV spectrophotometry and high performance liquid chromatography methods. Arab J Chem 10:1422–S1428CrossRefGoogle Scholar
  37. Zgoła-Grześkowiak A, Grześkowiak T (2011) Dispersive liquid-liquid microextraction. Trends Anal Chem 30:1382–1399CrossRefGoogle Scholar
  38. Zhao Y, Yu G, Chen S, Zhang S, Wang B, Huang J, Deng S, Wang Y (2017) Ozonation of antidepressant fluoxetine and its metabolite product norfluoxetine: kinetics, intermediates and toxicity. Chem Eng J 316:951–963CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Hanife Sari Erkan
    • 1
    Email author
  • Dotse Selali Chormey
    • 2
  • Abdulkadir Caglak
    • 1
  • Gamze Dalgic Bozyigit
    • 1
  • Esra Maltepe
    • 2
  • Güleda Onkal Engin
    • 1
  • Sezgin Bakırdere
    • 2
  1. 1.Department of Environmental Engineering, Faculty of Civil EngineeringYildiz Technical UniversityİstanbulTurkey
  2. 2.Department of Chemistry, Faculty of Art and ScienceYildiz Technical UniversityİstanbulTurkey

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