Binary Dispersive Liquid-Liquid Microextraction Strategy for Accurate and Precise Determination of Micropollutants in Lake, Well and Wastewater Matrices

  • Hanife Sari ErkanEmail author
  • Dotse Selali Chormey
  • Abdulkadir Caglak
  • Gamze Dalgic Bozyigit
  • Esra Maltepe
  • Güleda Onkal Engin
  • Sezgin Bakırdere


In this study, a binary mixture in dispersive liquid-liquid microextraction was used for the preconcentration and determination of selected pesticides, pharmaceutical and hormone by GC–MS. A Box–Behnken experimental design was used to optimize the amounts of binary mixture, dispersive solvent and salt. The optimum parameters obtained were dichloromethane/1,2-dichloroethane binary mixture (200 µL), ethanol (2.0 mL) and potassium nitrate (1.0 g). Analytical performance of each analyte was determined under the optimum conditions and the lowest and highest detection limits calculated were 0.43 and 5.9 ng/mL. Low relative standard deviations were obtained even in the lowest concentrations in linear calibration plots, signifying high precision for the sample preparation procedure and instrumental measurement. Accuracy of the developed method and applicability to real samples was tested on well, lake, hospital and municipal wastewater. The percent recoveries acquired at different spiked concentrations were satisfactory (89%–108%), validating the accuracy of the method for the quantification of the analytes in the selected matrices.


Pesticide B-DLLME GC–MS Wastewater Experimental design 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Hanife Sari Erkan
    • 1
    Email author
  • Dotse Selali Chormey
    • 2
  • Abdulkadir Caglak
    • 1
  • Gamze Dalgic Bozyigit
    • 1
  • Esra Maltepe
    • 2
  • Güleda Onkal Engin
    • 1
  • Sezgin Bakırdere
    • 2
  1. 1.Department of Environmental Engineering, Faculty of Civil EngineeringYildiz Technical UniversityİstanbulTurkey
  2. 2.Department of Chemistry, Faculty of Art and ScienceYildiz Technical UniversityİstanbulTurkey

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