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Evaluation of Acute Toxicity, Cytotoxicity and Genotoxicity of a Nickel Mining Waste to Oreochromis niloticus

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Abstract

The pyrometallurgical process of mining for obtaining ferronickel involves a stage of calcinations. At this stage a residue is generated described as a calcination dust of fine black grains. Analysis of this material revealed a significant presence of Fe, around 53,000 ppm and Ni, around 14,000, beyond of other metals as Al, Mn, and Cr. Adults and larvae of Oreochromis niloticus were used to evaluate acute toxicity, cytotoxicity and genotoxicity, and histopathological effects. The data obtained show absence of toxicity in concentrations of 5, 10 and 50% but a considerable potential for bioaccumulation in the fish’s body.

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Acknowledgments

The team is grateful to CT – Mineral CNPq of the Brazilian Ministry of Science and Technology (Contract no 409997/2006–4) and SEG-Embrapa for financial support.

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Correspondence to Eduardo Cyrino Oliveira-Filho.

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Oliveira-Filho, E.C., de Freitas Muniz, D.H., Ferreira, M.F.N. et al. Evaluation of Acute Toxicity, Cytotoxicity and Genotoxicity of a Nickel Mining Waste to Oreochromis niloticus . Bull Environ Contam Toxicol 85, 467–471 (2010). https://doi.org/10.1007/s00128-010-0118-6

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Keywords

  • Nickel mining
  • Ecotoxicity
  • Fish
  • Industrial waste
  • Aquatic toxicity