There has been increasing concern in regards to organophosphate (OP) pesticide exposure among farm workers and their families in Thailand’s agricultural areas. Therefore, the development of an analytical method for estimating OP pesticide exposure is necessary to allow for monitoring of OP pesticide exposures within these populations. This paper describes an analytical method developed to measure dialkylphosphate (DAP) metabolites in urine. The methods in this study are important in the biological monitoring of OP metabolites in agricultural families in Thailand and can be used as an initial guidance procedure in any environmental toxicological laboratory in Thailand.
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This study was supported by National Research Center for Environmental and Hazardous Waste Management (NRC-EHWM), Chulalongkorn University. The authors also thank the Reference Laboratory and Toxicology Center, Bureau of Occupational and Environmental Disease, Department of Disease Control, Ministry of Public Health, for providing the facilities and assistance in developing method for dialkylphosphate metabolite measurement. We also thank Dr. Dana Barr for her helpful suggestions in revising this manuscript. Support was also provided by NIEHS P30 ES05022.
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Petchuay, C., Thoumsang, S., Visuthismajarn, P. et al. Analytical Method Developed for Measurement of Dialkylphosphate Metabolites in Urine Collected from Children Non-Occupationally Exposed to Organophosphate Pesticides in an Agricultural Community in Thailand. Bull Environ Contam Toxicol 81, 401–405 (2008). https://doi.org/10.1007/s00128-008-9515-5
- Analytical method
- Non-occupational exposure