First-episode drug-induced psychosis: a medium term follow up study reveals a high-risk group

  • Kathleen Crebbin
  • Emma Mitford
  • Roger Paxton
  • Douglas Turkington
ORIGINAL PAPER

DOI: 10.1007/s00127-008-0490-2

Cite this article as:
Crebbin, K., Mitford, E., Paxton, R. et al. Soc Psychiat Epidemiol (2009) 44: 710. doi:10.1007/s00127-008-0490-2
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Abstract

Background

Little is known about first-episode drug-induced psychosis (F19.5).

Objectives

To examine the incidence, course, diagnostic stability, and outcomes of first-episode drug-induced psychosis (F19.5), and compare with first-episode schizophrenia (F20–21).

Method

An observational database was set up on all patients aged 16 and over with a first episode psychosis living in a county in Northern England between October 1998 and October 2005. Data were collected at presentation and annual follow-up. Information on patients with an ICD-10 diagnosis of either drug-induced psychosis (F19.5) or schizophrenia (F20) was compared.

Results

There was no significant difference between the two groups in levels of hospitalisation and violence. Patients with a drug-induced psychosis were more likely to lose contact with services, and a third developed a schizophrenia-spectrum disorder.

Conclusions

Increased attention should be paid to maintaining engagement with this high-risk group who have a high rate of transition to schizophrenia.

Keywords

drug-induced psychosis first-episode psychosis schizophrenia hospitalisation violence engagement with services 

Copyright information

© Steinkopff Verlag Darmstadt 2009

Authors and Affiliations

  • Kathleen Crebbin
    • 1
  • Emma Mitford
    • 1
  • Roger Paxton
    • 1
  • Douglas Turkington
    • 1
  1. 1.Northumberland, Tyne and Wear NHS TrustMorpethUK

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