First-episode drug-induced psychosis: a medium term follow up study reveals a high-risk group
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- Crebbin, K., Mitford, E., Paxton, R. et al. Soc Psychiat Epidemiol (2009) 44: 710. doi:10.1007/s00127-008-0490-2
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Little is known about first-episode drug-induced psychosis (F19.5).
To examine the incidence, course, diagnostic stability, and outcomes of first-episode drug-induced psychosis (F19.5), and compare with first-episode schizophrenia (F20–21).
An observational database was set up on all patients aged 16 and over with a first episode psychosis living in a county in Northern England between October 1998 and October 2005. Data were collected at presentation and annual follow-up. Information on patients with an ICD-10 diagnosis of either drug-induced psychosis (F19.5) or schizophrenia (F20) was compared.
There was no significant difference between the two groups in levels of hospitalisation and violence. Patients with a drug-induced psychosis were more likely to lose contact with services, and a third developed a schizophrenia-spectrum disorder.
Increased attention should be paid to maintaining engagement with this high-risk group who have a high rate of transition to schizophrenia.