Expression of Concern: Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRβ/IRS-1 and Akt
Expression of Concern to: Diabetologia
On the basis of the recommendation of the EASD’s Scientific Integrity Panel, the Editor-in-Chief is issuing this expression of concern to alert readers to questions about the reliability of some of the data in the article cited above.
The journal has been unable to obtain the high resolution image used in Ropelle et al from the corresponding author, Dr Carvalheira, and the editorial office of Diabetes no longer had a copy of this image. It has therefore not been possible to use image forensics to conclusively confirm or refute this concern.
In line with guidelines issued by the Committee on Publication Ethics (COPE), the journal has informed the corresponding author, Mario Saad, of this concern. The University of Campinas (São Paulo, Brazil) was asked, in March 2016, to undertake an institutional investigation. As no results from this investigation have been forthcoming this expression of concern is being issued to alert readers to exercise caution when interpreting the content and conclusions of this article. This expression of concern will remain in place until such a time as further evidence is available.