Diabetologia

, Volume 60, Issue 4, pp 756–757 | Cite as

Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter]

  • Marcus Lundberg
  • Peter Seiron
  • Sofie Ingvast
  • Olle Korsgren
  • Oskar Skog
Letter
  • 259 Downloads

Keywords

CD45 Immunopathology Inflammation Insulitis Islets Macrophages Pancreas T cells Type 1 diabetes Type 2 diabetes 

Notes

Acknowledgements

We wish to thank everyone in the Nordic Network for Clinical Islet Transplantation who was involved in the procurement of pancreases and islets. We also give our deepest gratitude to all organ donors.

Funding

Work in the authors’ laboratories was supported by the PEVNET Study Group funded by the European Union’s Seventh Framework Programme [FP7/2007-2013] under grant agreement number 261441 PEVNET, the Swedish Medical Research Council (K2015-54X-12219-19-4), the Diabetes Wellness Foundation, the Family Ernfors Foundation, the Novo Nordisk Foundation, the Åke Wiberg Foundation, the Tore Nilsson Foundation, the Swedish Diabetes Association, Gillbergska Stiftelsen, and Barndiabetesfonden. Human pancreatic biopsies and isolated islets were obtained from the Nordic Network for Clinical Islet Transplantation, supported by the Swedish national strategic research initiative Excellence of Diabetes Research in Sweden (EXODIAB) and the JDRF.

Duality of interests

The authors declare that there is no duality of interest associated with this manuscript.

Contribution statement

All authors were responsible for drafting the letter and revising it critically for important intellectual content. All authors approved the version to be published.

References

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Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Marcus Lundberg
    • 1
  • Peter Seiron
    • 1
  • Sofie Ingvast
    • 1
  • Olle Korsgren
    • 1
  • Oskar Skog
    • 1
  1. 1.Department of Immunology, Genetics and Pathology, The Rudbeck Laboratory C11, Clinical ImmunologyUppsala UniversityUppsalaSweden

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