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Diabetologia

, Volume 57, Issue 3, pp 645–646 | Cite as

Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry?

  • Sara F. Hansson
  • Stella Korsgren
  • Fredrik Pontén
  • Olle Korsgren
Letter

Keywords

Enterovirus Immunohistochemistry Type 1 diabetes VP-1 

Abbreviations

IHC

Immunohistochemistry

mAb

Monoclonal antibody

VP1

Viral peptide 1

Notes

Acknowledgements

Human pancreatic islets were obtained from the Nordic Network for Clinical Islet Transplantation, supported by the Swedish national strategic research initiative EXODIAB (Excellence of Diabetes Research in Sweden) and the JDRF.

Funding

This study was supported by grants from the Swedish Medical Research Council (65X-12219-15-6), the Knut and Alice Wallenberg Research Foundation, EU-FP7-Health 2010 PEVNET 261441 and the Novo Nordisk Foundation; OK’s position is in part supported by the National Institutes of Health (2U01AI065192-06).

Duality of interest

The authors declare that there is no duality of interest associated with this manuscript.

Contribution statement

All authors were responsible for the conception and design of the manuscript, drafting the article and revising it critically for important intellectual content. All authors approved the version to be published.

References

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Sara F. Hansson
    • 1
  • Stella Korsgren
    • 2
  • Fredrik Pontén
    • 2
  • Olle Korsgren
    • 2
  1. 1.Proteomics Core FacilityUniversity of GothenburgGothenburgSweden
  2. 2.Department of Immunology, Genetics and PathologyUppsala UniversityUppsalaSweden

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