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Theoretical and Applied Genetics

, Volume 99, Issue 7–8, pp 1143–1148 | Cite as

Marker-assisted recurrent selection for cumulating additive and interactive QTLs in recombinant inbred lines

  • G. Charmet
  • N. Robert
  • M. R. Perretant
  • G. Gay
  • P. Sourdille
  • C. Groos
  • S. Bernard
  • M. Bernard
Original Article

Abstract 

A computer program has been designed to manage marker information in recombinant inbred-line populations. The objective is to select pairs of inbred lines (either recombinant-inbred or doubled-haploid) to be intercrossed, in order to accumulate all or most favourable alleles, either with additive effects or with interactive effects. The population size required to have a 95% chance of obtaining the best line from a given cross is computed, taking into account the number of QTLs and the probability that no recombination event occurs in any of the QTL confidence intervals. It is shown that the accuracy of QTL location greatly affects selection efficiency and that a recurrent selection scheme is highly preferable for pyramiding many QTLs. An application to the bread-making quality improvement of wheat is presented.

Key words Molecular markers Doubled-haploid Molecular score Confidence intervals 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • G. Charmet
    • 1
  • N. Robert
    • 1
  • M. R. Perretant
    • 1
  • G. Gay
    • 1
  • P. Sourdille
    • 1
  • C. Groos
    • 1
  • S. Bernard
    • 1
  • M. Bernard
    • 1
  1. 1.INRA, plant breeding station, 204 avenue du Brézet, F63039 Clermont-Ferrand cedex, FranceFR

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