Theoretical and Applied Genetics

, Volume 132, Issue 3, pp 713–732 | Cite as

Contribution of recent technological advances to future resistance breeding

  • Javier Sánchez-MartínEmail author
  • Beat Keller
Review Article
Part of the following topical collections:
  1. New technologies for plant breeding


The development of durable host resistance strategies to control crop diseases is a primary need for sustainable agricultural production in the future. This article highlights the potential of recent progress in the understanding of host resistance for future cereal breeding. Much of the novel work is based on advancements in large-scale sequencing and genomics, rapid gene isolation techniques and high-throughput molecular marker technologies. Moreover, emerging applications on the pathogen side like effector identification or field pathogenomics are discussed. The combination of knowledge from both sides of cereal pathosystems will result in new approaches for resistance breeding. We describe future applications and innovative strategies to implement effective and durable strategies to combat diseases of major cereal crops while reducing pesticide dependency.



We apologize to the authors whose work was not mentioned here due to the space constraints. JSM is partially supported by the University Research Priority Programs (URPP) of the University of Zurich. We would like to thank Victoria Widrig for support with the preparation of Fig. 2. Finally, we would like to thanks to the anonymous reviewer for many valuable comments.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Plant and Microbial BiologyUniversity of ZürichZurichSwitzerland

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