Theoretical and Applied Genetics

, Volume 130, Issue 12, pp 2479–2490 | Cite as

Copy number variation and disease resistance in plants

  • Aria Dolatabadian
  • Dhwani Apurva Patel
  • David Edwards
  • Jacqueline BatleyEmail author


Plant genome diversity varies from single nucleotide polymorphisms to large-scale deletions, insertions, duplications, or re-arrangements. These re-arrangements of sequences resulting from duplication, gains or losses of DNA segments are termed copy number variations (CNVs). During the last decade, numerous studies have emphasized the importance of CNVs as a factor affecting human phenotype; in particular, CNVs have been associated with risks for several severe diseases. In plants, the exploration of the extent and role of CNVs in resistance against pathogens and pests is just beginning. Since CNVs are likely to be associated with disease resistance in plants, an understanding of the distribution of CNVs could assist in the identification of novel plant disease-resistance genes. In this paper, we review existing information about CNVs; their importance, role and function, as well as their association with disease resistance in plants.



The authors thank the Australian Research Council Projects FT130100604, DP1601004497, LP140100537, LP160100030 and LP130100925.

Compliance with ethical standards

Conflict of interest

The authors declare no conflicts of interest.


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Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  1. 1.School of Biological Sciences and Institute of AgricultureUniversity of Western AustraliaCrawleyAustralia

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