Theoretical and Applied Genetics

, Volume 105, Issue 2–3, pp 423–430 | Cite as

Structure and expression of the Zea mays mutS-homologs Mus1 and Mus2

  •  M. Horwath
  •  W. Kramer
  •  R. Kunze

Abstract.

DNA mismatch repair proteins play an important role in maintaining the integrity of the genetic information during replication and homologous recombination. The MutS-homologous (MSH) and MutL-homologous (MLH) proteins are highly conserved among all prokaryotes and eukaryotes. We have isolated two mutS homologous genes from Zea mays, named Mus1 and Mus2. Phylogenetic analysis identifies Mus1 as a member of the MSH2 protein family. Mus2 is an ortholog of the Arabidopsis thaliana MSH7 protein and belongs to a subgroup of MSH proteins that is possibly plant-specific. Mus1 and Mus2 are expressed at very low levels. Mus1 is located on chromosome 7L near locus b32B, and mus2 maps on chromosome 3S.

Zea mays DNA mismatch repair MutS MSH protein 

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Copyright information

© Springer-Verlag 2002

Authors and Affiliations

  •  M. Horwath
    • 1
  •  W. Kramer
    • 2
  •  R. Kunze
    • 1
  1. 1.Institute of Genetics, University of Munich, Maria-Ward-Strasse 1a, 80638 München, Germany
  2. 2.Department of Molecular Genetics and Preparative Molecular Biology, Institute for Microbiology and Genetics, Georg-August University, Göttingen, Grisebachstrasse 8, D-37077 Göttingen, Germany
  3. 3.Present address: Icon Genetics AG, Blumenstrasse 16, 85354 Freising, Germany
  4. 4.Present address: Botanical Institute, University of Cologne, Gyrhofstrasse 15, 50931 Köln, Germany

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