Der Urologe

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Unzureichende Studienergebnisse und fehlender positiver klinischer Nutzen der ketogenen Diät


Ketogenic diet: insufficient study results and lack of positive clinical benefits



P. Maisch, J. E. Gschwend und M. Retz geben an, dass kein Interessenkonflikt besteht.


  1. 1.
    Dirx MJM, Zeegers MPA, Dagnelie PC, Van Den Bogaard T, Van Den Brandt PA (2003) Energy restriction and the risk of spontaneous mammary tumors in mice: a meta-analysis. Int J Cancer 106:766–770CrossRefPubMedGoogle Scholar
  2. 2.
    Lv M, Zhu X, Wang H, Wang F, Guan W (2014) Roles of caloric restriction, ketogenic diet and intermittent fasting during initiation, progression and metastasis of cancer in animal models: a systematic review and meta-analysis. PLoS ONE 9:e115147CrossRefPubMedPubMedCentralGoogle Scholar
  3. 3.
    Klement RJ, Champ CE, Otto C, Kämmerer U (2016) Anti-tumor effects of ketogenic diets in mice: a meta-analysis. PLoS ONE 11:e155050CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    Santos JG, Da Cruz WMS, Schönthal AH, Salazar M, Fontes CAP, Quirico-Santos T et al (2018) Efficacy of a ketogenic diet with concomitant intranasal perillyl alcohol as a novel strategy for the therapy of recurrent glioblastoma. Oncol Lett 15:1263–1270PubMedGoogle Scholar
  5. 5.
    Klement RJ (2016) Fasten als therapeutische Ergänzung. Info Onkol 19:14–16CrossRefGoogle Scholar
  6. 6.
    Klement RJ (2016) Fasten als Nebenwirkungsmanagement? Info Onkol 19:22–24CrossRefGoogle Scholar
  7. 7.
    de Groot S, Vreeswijk MP, Welters MJ, Gravesteijn G, Boei JJ, Jochems A et al (2015) The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study. BMC Cancer 15:652CrossRefPubMedPubMedCentralGoogle Scholar
  8. 8.
    Dorff TB, Groshen S, Garcia A, Shah M, Tsao-Wei D, Pham H et al (2016) Safety and feasibility of fasting in combination with platinum-based chemotherapy. BMC Cancer 16:360CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Klement RJ, Fink MK (2016) Dietary and pharmacological modification of the insulin/IGF-system: exploiting the full repertoire against cancer. Oncogenesis 5:e193CrossRefPubMedPubMedCentralGoogle Scholar
  10. 10.
    Jansen N, Walach H (2016) The development of tumours under a ketogenic diet in association with the novel tumour marker TKTL1: a case series in general practice. Oncol Lett 11:584–592CrossRefPubMedGoogle Scholar
  11. 11.
    Klement RJ (2017) Beneficial effects of ketogenic diets for cancer patients: a realist review with focus on evidence and confirmation. Med Oncol 34:132CrossRefPubMedGoogle Scholar
  12. 12.
    Smith GCS, Pell JP (2003) Parachute use to prevent death and major trauma related to gravitationalchallenge: systematic review of randomised controlled trials. BMJ 327:1459–1461CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2018

Authors and Affiliations

  1. 1.Klinik und Poliklinik für Urologie, Klinikum rechts der IsarTechnische Universität MünchenMünchenDeutschland
  2. 2.Arbeitsgemeinschaft Urologische Onkologie (AUO)Deutsche Krebsgesellschaft e. V.BerlinDeutschland

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