Der Radiologe

, Volume 58, Supplement 1, pp 14–19 | Cite as

Diffusion-weighted breast imaging

  • K. Deike-Hofmann
  • T. Kuder
  • F. König
  • D. Paech
  • C. Dreher
  • S. Delorme
  • H.‑P. Schlemmer
  • S. Bickelhaupt


Magnetic resonance imaging (MRI) of the breast represents one of the most sensitive imaging modalities in breast cancer detection. Diffusion-weighted imaging (DWI) is a sequence variation introduced as a complementary MRI technique that relies on mapping the diffusion process of water molecules thereby providing additional information about the underlying tissue. Since water diffusion is more restricted in most malignant tumors than in benign ones owing to the higher cellularity of the rapidly proliferating neoplasia, DWI has the potential to contribute to the identification and characterization of suspicious breast lesions. Thus, DWI might increase the diagnostic accuracy of breast MRI and its clinical value. Future applications including optimized DWI sequences, technical developments in MR devices, and the application of radiomics/artificial intelligence algorithms may expand the potential of DWI in breast imaging beyond its current supplementary role.


Breast neoplasms Diffusion magnetic resonance imaging Diagnostic imaging Image interpretation, computer-assisted Classification 

Diffusionsgewichtete MRT der Brust


Die Magnetresonanztomographie (MRT) der weiblichen Brust ist eines der sensitivsten bildgebenden Verfahren in der Brustkrebsdiagnostik. Die diffusionsgewichtete MRT (DWI) ist eine MRT-Sequenz, die die Bewegung von Wassermolekülen im Untersuchungsgebiet erfasst. Da diese in den meisten malignen Tumoren eingeschränkt ist, kann die DWI einen zusätzlichen Beitrag zur Identifikation und Charakterisierung von auffälligen Brustläsionen liefern und so perspektivisch den diagnostischen Stellenwert der MRT in der Brustkrebsdiagnostik weiter erhöhen. Zukünftige Entwicklungen im Bereich der Sequenzoptimierung, MR-Gerätetechnik und der intelligenten Softwarealgorithmen haben das Potenzial, die Rolle der DWI in der Brustbildgebung weiter zu steigern.


Neoplasien der Brust Diffusions-gewichtete MRT Diagnostische Bildgebung Computer-unterstützte Bildinterpretation Klassifikation 


Compliance with ethical guidelines

Conflict of interest

K. Deike-Hofmann, T. Kuder, F. König, D. Paech, C. Dreher, S. Delorme, H.-P. Schlemmer, and S. Bickelhaupt declare that they have no competing interests.

This article does not contain any studies with human participants or animals performed by any of the authors.

The supplement containing this article is not sponsored by industry.


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Copyright information

© Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2018

Authors and Affiliations

  • K. Deike-Hofmann
    • 1
  • T. Kuder
    • 2
  • F. König
    • 1
  • D. Paech
    • 1
  • C. Dreher
    • 1
  • S. Delorme
    • 1
  • H.‑P. Schlemmer
    • 1
  • S. Bickelhaupt
    • 1
  1. 1.Department of RadiologyGerman Cancer Research CenterHeidelbergGermany
  2. 2.Department of Medical PhysicsGerman Cancer Research CenterHeidelbergGermany

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