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Bildgebende Diagnostik und Visualisierung von Bestrahlungsfolgen bei Weichteilsarkomen

Diagnostic imaging and visualization of radiation treatment effects in soft tissue sarcomas

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Zusammenfassung:

Weichteilsarkome sind seltene Tumoren und machen nur etwa 1% der malignen Tumoren im Erwachsenenalter aus. Der therapeutische Erfolg beruht bisher wesentlich auf aggressiver chirurgischer Intervention. Die Indikation zur adjuvanten Strahlentherapie ist v. a. vom Grading des Tumors abhängig. Für die Planung einer möglichst vollständigen Tumorentfernung besitzt die bildgebende Diagnostik zentralen Stellenwert. Neben morphologischen Verfahren werden funktionell-bildbasierte Verfahren insbesondere zum Therapiemonitoring weiter an Bedeutung zunehmen.

Abstract

Soft tissue sarcomas are rare malignant neoplasms accounting for only 1% of malignant tumors in adults. Complete surgical resection of tumors is the key to therapeutic success. Indications for adjuvant radiation therapy vary according to the lesion grade. Comprehensive diagnostic imaging significantly contributes to successful preoperative planning procedures. Besides morphological imaging, functional imaging strategies will have an increasing impact on individual risk assessment and contribute to optimized, non-invasive treatment response monitoring.

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Correspondence to PD Dr. F. Berger.

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Berger, F., Reiser, M. & Graser, A. Bildgebende Diagnostik und Visualisierung von Bestrahlungsfolgen bei Weichteilsarkomen. Radiologe 52, 222–228 (2012). https://doi.org/10.1007/s00117-011-2193-z

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Schlüsselwörter

  • Weichteilsarkom
  • Therapieresponse
  • Monitoring
  • MRT-Perfusion
  • Fluordeoxyglukose-Positronenemissionstomographie (FDG-PET)

Keywords

  • Soft tissue sarcoma
  • Treatment response
  • Monitoring
  • Magnetic resonance imaging perfusion
  • Fluorodeoxyglucose positron emission tomography (FDG-PET)