Naturwissenschaften

, Volume 88, Issue 3, pp 113–116

Differentially expressed regulatory genes in honey bee caste development

  • C. Hepperle
  • K. Hartfelder
Short Communication

DOI: 10.1007/s001140000196

Cite this article as:
Hepperle, C. & Hartfelder, K. Naturwissenschaften (2001) 88: 113. doi:10.1007/s001140000196

Abstract.

In the honey bee, an eminently fertile queen with up to 200 ovarioles per ovary monopolizes colony level reproduction. In contrast, worker bees have only few ovarioles and are essentially sterile. This phenotype divergence is a result of caste-specifically modulated juvenile hormone and ecdysteroid titers in larval development. In this study we employed a differential-display reverse transcription (DDRT)-PCR protocol to detect ecdysteroid-regulated gene expression during a critical phase of caste development. We identified a Ftz-F1 homolog and a Cut-like transcript. Ftz-F1 could be a putative element of the metamorphic ecdysone response cascade of bees, whereas Cut-like proteins are described as transcription factors involved in maintaining cellular differentiation states. The downregulation of both factors can be interpreted as steps in the metamorphic degradation of ovarioles in worker-bee ovaries.

Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  • C. Hepperle
    • 1
  • K. Hartfelder
    • 1
  1. 1.Lehrstuhl Entwicklungsphysiologie, Zoologisches Institut, Universität Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany
  2. 2.Present address: Molecular Sciences, Department of Genetics, University of Adelaide, Adelaide SA 5005, Australia
  3. 3.Present address: Departamento de Biologia, Universidade de São Paulo, 14040-901 Ribeirão Preto, Brazil

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