Der Internist

, Volume 60, Issue 2, pp 209–216 | Cite as

Stellenwert von Acetylsalicylsäure in der Primärprävention

ASCEND, ARRIVE and ASPREE as well as a meta-analysis by Rothwell et al.
  • K. SchrörEmail author
  • S. Nitschmann
Klinische Studien


The ASCEND Study Collaborative Group (2018) Effects of aspirin for primary prevention in persons with diabetes mellitus. N Engl J Med 379:1529–1539

Gaziano JM, Brotons C, Coppolecchia R et al (2018) Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial. Lancet 392:1036–1046

McNeil JJ, Wood RL, Nelson MR et al for the ASPREE Investigator-Group (2018) Effect of aspirin on disability-free survival in the healthy elderly. N Engl J Med

McNeil JJ, Nelson MR, Wood RL et al for the ASPREE Investigator-Group (2018) Effect of aspirin on all-cause mortality in the healthy elderly. N Engl J Med

McNeil JJ, Wolfe R, Wood RL et al for the ASPREE Investigator-Group (2018) Effect of aspirin on cardiovascular events and bleeding in the healthy elderly. N Engl J Med

Importance of acetylsalicylic acid in primary prevention

ASCEND, ARRIVE and ASPREE as well as a meta-analysis by Rothwell et al.


Einhaltung ethischer Richtlinien


K. Schrör und S. Nitschmann geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.


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Copyright information

© Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2019

Authors and Affiliations

  1. 1.Institut für Pharmakologie und Klinische PharmakologieUniversitätsklinikum DüsseldorfDüsseldorfDeutschland
  2. 2.LippetalDeutschland

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