Der Internist

, Volume 54, Issue 11, pp 1376–1382 | Cite as

Polydipsie, zunehmende Müdigkeit und große mediastinale Raumforderung bei einer 49-jährigen Patientin

  • T. Friedrich
  • C. Rust
  • G. Bischoff
  • J.G. Wechsler
  • T. Jakobs
  • N. Woehrle
  • F. Brettner
  • H. Winter
  • M. Angele
  • B. Wendl
Kasuistiken

Zusammenfassung

Eine 49-jährige Patientin stellte sich mit einem diffusen Beschwerdebild mit Polydipsie, seit Wochen zunehmender Müdigkeit und unspezifischen abdominellen Schmerzen vor. Bei Kalzium im Serum von 5,30 mmol/l (RB: 2,00–2,60), Parathormon von > 2500,0 ng/l (RB: 15,0–68,0) und einer mediastinalen Raumforderung wurde die Diagnose einer hyperkalzämischen Krise auf dem Boden eines primären Hyperparathyreoidismus gestellt. Nach intensivstationärer Stabilisierung erfolgte die Parathyreoidektomie eines Nebenschilddrüsenadenoms. Der postoperative Verlauf war weitgehend komplikationslos.

Schlüsselwörter

Kalzium Hyperkalzämie Nebenschilddrüsenadenom Parathormon Primärer Hyperparathyreoidismus 

Polydipsia, increasing fatigue and a huge mediastinal tumor in a 49-year-old woman

Abstract

A 49-year-old woman presented with unspecific symptoms including polydipsia, increasing fatigue for several weeks, and vague abdominal pain. Serum calcium (5.30 mmol/l; normal range 2.00–2.60) and parathyroid hormone levels (> 2500.0 ng/l; normal range 15.0–68.0) were extremely elevated. Imaging studies showed a huge mediastinal tumor. Based on these findings a hypercalcemic crisis caused by primary hyperparathyroidism was diagnosed. After intensive care treatment and further diagnostic procedures, the patient’s parathyroid adenoma was removed by parathyroidectomy. The postoperative course was uneventful.

Keywords

Calcium Hypercalcemia Parathyroid adenoma Parathyroid hormone Hyperparathyroidism, primary 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • T. Friedrich
    • 1
  • C. Rust
    • 1
  • G. Bischoff
    • 1
  • J.G. Wechsler
    • 1
  • T. Jakobs
    • 2
  • N. Woehrle
    • 2
  • F. Brettner
    • 3
  • H. Winter
    • 4
  • M. Angele
    • 4
  • B. Wendl
    • 1
  1. 1.Abteilung Innere Medizin IKrankenhaus Barmherzige Brüder MünchenMünchenDeutschland
  2. 2.Abteilung RadiologieKrankenhaus Barmherzige Brüder MünchenMünchenDeutschland
  3. 3.Abteilung IntensivmedizinKrankenhaus Barmherzige Brüder MünchenMünchenDeutschland
  4. 4.Allgemein-, Viszeral-, Transplantations-. Gefäss- und Thoraxchirurgie – Campus GroßhadernKlinikum der Universität MünchenMünchenDeutschland

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