Der Internist

, Volume 54, Issue 10, pp 1171–1184

Kardiologische Krankheitsbilder

Schwerpunkt
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Zusammenfassung

Die Kenntnis seltener kardiologischer Krankheitsbilder ist für den klinischen Alltag von großer Bedeutung, da sich durch eine frühe Diagnosestellung, optimales Monitoring der Patienten sowie eine frühzeitige adäquate Therapieeinleitung schwere Krankheitsverläufe und Todesfälle verhindern lassen. In diesem Beitrag werden eine wichtige rhythmologische Erkrankung, die arrhythmogene rechtsventrikuläre Kardiomyopathie, sowie mit der Tako-Tsubo-(Stress-)Kardiomyopathie und dem Aortenaneurysma bei Marfan-Syndrom 2 bedeutende strukturelle Erkrankungen vorgestellt. Direkte Implikationen für die klinische Praxis werden näher erläutert.

Schlüsselwörter

Arrhythmogene rechtsventrikuläre Kardiomyopathie Marfan-Syndrom Tako-Tsubo-Kardiomyopathie Aortenaneurysma Guideline 

Cardiological diseases

Abstract

Knowledge of rare but important clinical disease symptoms in cardiology is of vital importance in the daily routine as severe courses of disease as well as death may be prevented by early diagnosis, effective monitoring and timely initiation of an adequate therapy. In this article an important rhythmological disease, arrhythmogenic right ventricular cardiomyopathy, as well as two significant structural diseases, takotsubo (stress-related) cardiomyopathy and aortic aneurysm related to Marfan syndrome, as well as their implications for clinical practice will be presented.

Keywords

Arrhythmogenic right ventricular cardiomyopathy Marfan syndrome Takotsubo cardiomyopathy Aortic aneurysm Guideline 

Literatur

  1. 1.
    Akashi YJ, Goldstein DS, Barbaro G, Ueyama T (2008) Takotsubo cardiomyopathy: a new form of acute, reversible heart failure. Circulation 118:2754–2762PubMedCrossRefGoogle Scholar
  2. 2.
    Basso C et al (1997) Morbid anatomy. In: Nava A et al (Hrsg) Arrhythmogenic right ventricular cardiomyopathy – dysplasia. Elsevier, Amsterdam, S 71–86Google Scholar
  3. 3.
    Brooke BS, Habashi JP, Judge DP et al (2008) Angiotensin II blockade and aortic-root dilation in Marfan’s syndrome. N Engl J Med 358:2787–2795PubMedCrossRefGoogle Scholar
  4. 4.
    Corrado D, Fontaine G, Marcus FI et al (2000) Arrhythmogenic right ventricular dysplasia/cardiomyopathy: need for an international registry. Circulation 101:E101–106PubMedCrossRefGoogle Scholar
  5. 5.
    Corrado D, Basso C, Schiavon M, Thiene G (1998) Screening for hypertrophic cardiomyopathy in young athletes. N Engl J Med 339:364–369PubMedCrossRefGoogle Scholar
  6. 6.
    Dalal D, Nasir K, Bomma C et al (2005) Arrhythmogenic right ventricular dysplasia: a United States experience. Circulation 112:3823–3832PubMedCrossRefGoogle Scholar
  7. 7.
    Deac M, Alpendurada F, Fanaie F et al (2013) Prognostic value of cardiovascular magnetic resonance in patients with suspected arrhythmogenic right ventricular cardiomyopathy. Int J Cardiol. DOI 10.1016/j.ijcard.2013.04.208. (Epub ahead of print)Google Scholar
  8. 8.
    Elesber AA, Prasad A, Lennon RJ et al (2007) Four-year recurrence rate and prognosis of the apical ballooning syndrome. J Am Coll Cardiol 50:448–452PubMedCrossRefGoogle Scholar
  9. 9.
    Gemayel C, Pelliccia A, Thompson PD (2001) Arrhythmogenic right ventricular cardiomyopathy. J Am Coll Cardiol 38:1773–1781PubMedCrossRefGoogle Scholar
  10. 10.
    Gianni M, Dentali F, Grandi AM et al (2006) Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review. Eur Heart J 27:1523–1529PubMedCrossRefGoogle Scholar
  11. 11.
    Gott VL, Greene PS, Alejo DE et al (1999) Replacement of the aortic root in patients with Marfan’s syndrome. N Engl J Med 340:1307–1313PubMedCrossRefGoogle Scholar
  12. 12.
    Groenink M, de Roos A, Mulder BJ et al (2001) Biophysical properties of the normal-sized aorta in patients with Marfan syndrome: evaluation with MR flow mapping. Radiology 219:535–540PubMedGoogle Scholar
  13. 13.
    Hiratzka LF, Bakris GL, Beckman JA et al (2010) 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with Thoracic Aortic Disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine.. Circulation 121:e266–369PubMedCrossRefGoogle Scholar
  14. 14.
    Hulot JS, Jouven X, Empana JP et al (2004) Natural history and risk stratification of arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circulation 110:1879–1884PubMedCrossRefGoogle Scholar
  15. 15.
    Marcus F, McKenna WJ, Sherrill D et al (2010) Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the task force criteria. Circulation 121:1533–1541PubMedCrossRefGoogle Scholar
  16. 16.
    Nava A, Bauce B, Basso C et al (2000) Clinical profile and long-term follow-up of 37 families with arrhythmogenic right ventricular cardiomyopathy. J Am Coll Cardiol 36:2226–2233PubMedCrossRefGoogle Scholar
  17. 17.
    Paur H, Wright PT, Sikkel MB et al (2012) High levels of circulating epinephrine trigger apical cardiodepression in aβ2-adrenergic receptor/Gi-dependent manner: a new model of Takotsubo cardiomyopathy. Circulation 126(6):697–706PubMedCrossRefGoogle Scholar
  18. 18.
    Prasad A, Lerman A, Rihal CS (2008) Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction. Am Heart J 155:408–417PubMedCrossRefGoogle Scholar
  19. 19.
    Roguin A, Bomma CS, Nasir K et al (2004) Implantable cardioverter-defibrillators in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy. J Am Coll Cardiol 43:1843–1852PubMedCrossRefGoogle Scholar
  20. 20.
    Rybczynski M, Mir TS, Sheikhzadeh S et al (2010) Frequency and age-related course of mitral valve dysfunction in the Marfan syndrome. Am J Cardiol 106:1048–1053PubMedCrossRefGoogle Scholar
  21. 21.
    Sharkey SW, Lesser JR, Zenovich AG et al (2005) Acute and reversible cardiomyopathy provoked by stress in women from the United States. Circulation 111:472–479PubMedCrossRefGoogle Scholar
  22. 22.
    Tabib A, Loire R, Chalabreysse L et al (2003) Circumstances of death and gross and microscopic observations in a series of 200 cases of sudden death associated with arrhythmogenic right ventricular cardiomyopathy and/or dysplasia. Circulation 108:3000–3005PubMedCrossRefGoogle Scholar
  23. 23.
    Tsuchihashi K, Ueshima K, Uchida T et al (2001) Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina Pectoris-Myocardial Infarction Investigations in Japan. J Am Coll Cardiol 38:11–18PubMedCrossRefGoogle Scholar
  24. 24.
    Turrini P, Corrado D, Basso C et al (2003) Noninvasive risk stratification in arrhythmogenic right ventricular cardiomyopathy. Ann Noninvasive Electrocardiol 8:161–169PubMedCrossRefGoogle Scholar
  25. 25.
    Verma A, Kilicaslan F, Schweikert RA et al (2005) Short- and long-term success of substrate-based mapping and ablation of ventricular tachycardia in arrhythmogenic right ventricular dysplasia. Circulation 111:3209–3216PubMedCrossRefGoogle Scholar
  26. 26.
    Wichter T, Paul M, Wollmann C et al (2004) Implantable cardioverter-defibrillator therapy in arrhythmogenic right ventricular cardiomyopathy: single-center experience of long-term follow-up and complication in 60 patients. Circulation 109:1503–1508PubMedCrossRefGoogle Scholar
  27. 27.
    Wichter T, Schulze-Bahr E, Eckardt L et al (2002) Molecular mechanisms of inherited ventricular arrhythmias. Herz 27:712–739PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Medizinische Klinik und Poliklinik IKlinikum der Ludwig-Maximilians-UniversitätMünchenDeutschland

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